Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control study
Background: Identifying the risk factors for the neurological deficit in spine tuberculosis would help surgeons in deciding on early surgery, thus reducing the morbidity related to neurological deficit. The main objective of our study was to predict the risk of neurological deficit in patients with...
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| Format: | Article |
| Language: | English |
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EDP Sciences
2021-01-01
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| Series: | SICOT-J |
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| Online Access: | https://www.sicot-j.org/articles/sicotj/full_html/2021/01/sicotj200148/sicotj200148.html |
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| author | Mittal Samarth Yadav Gagandeep Ahuja Kaustubh Ifthekar Syed Sarkar Bhaskar Kandwal Pankaj |
| author_facet | Mittal Samarth Yadav Gagandeep Ahuja Kaustubh Ifthekar Syed Sarkar Bhaskar Kandwal Pankaj |
| author_sort | Mittal Samarth |
| collection | DOAJ |
| description | Background: Identifying the risk factors for the neurological deficit in spine tuberculosis would help surgeons in deciding on early surgery, thus reducing the morbidity related to neurological deficit. The main objective of our study was to predict the risk of neurological deficit in patients with spinal tuberculosis (TB). Methods: The demographic, clinical, radiological (X-ray and MRI) data of 105 patients with active spine TB were retrospectively analyzed. Patients were divided into two groups – with a neurological deficit (n = 52) as Group A and those without deficit (n = 53) as Group B. Univariate and multivariate logistic regression analysis was used to predict the risk factors for the neurological deficit. Results: The mean age of the patients was 38.1 years. The most common location of disease was dorsal region (35.2%). Paradiscal (77%) was the most common type of involvement. A statistically significant difference (p < 0.05) was noted in the location of disease, presence of cord compression, kyphosis, cord oedema, loss of CSF anterior to the cord, and degree of canal compromise or canal encroachment between two groups. Multivariate analysis revealed kyphosis > 30° (OR – 3.92, CI – 1.21–12.7, p – 0.023), canal encroachment > 50% (OR – 7.34, CI – 2.32–23.17, p – 0.001), and cord oedema (OR – 11.93, CI – 1.24–114.05, p – 0.03) as independent risk factors for predicting the risk of neurological deficit. Conclusion: Kyphosis > 30°, cord oedema, and canal encroachment (>50%) significantly predicted neurological deficit in patients with spine TB. Early surgery should be considered with all these risk factors to prevent a neurological deficit. |
| first_indexed | 2024-12-13T17:40:36Z |
| format | Article |
| id | doaj.art-11dff876077049608c1762a7ced35bf7 |
| institution | Directory Open Access Journal |
| issn | 2426-8887 |
| language | English |
| last_indexed | 2024-12-13T17:40:36Z |
| publishDate | 2021-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | SICOT-J |
| spelling | doaj.art-11dff876077049608c1762a7ced35bf72022-12-21T23:36:45ZengEDP SciencesSICOT-J2426-88872021-01-017710.1051/sicotj/2021002sicotj200148Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control studyMittal Samarth0https://orcid.org/0000-0003-3528-0949Yadav Gagandeep1Ahuja Kaustubh2Ifthekar Syed3https://orcid.org/0000-0002-3546-5962Sarkar Bhaskar4https://orcid.org/0000-0002-1317-534XKandwal Pankaj5Senior Resident, AIIMS RishikeshDepartment of Orthopaedics, AIIMS RishikeshSenior Resident, AIIMS RishikeshSenior Resident, AIIMS RishikeshAssistant Professor, AIIMS RishikeshAdditional Professor, Consultant Spine Surgeon, AIIMS RishikeshBackground: Identifying the risk factors for the neurological deficit in spine tuberculosis would help surgeons in deciding on early surgery, thus reducing the morbidity related to neurological deficit. The main objective of our study was to predict the risk of neurological deficit in patients with spinal tuberculosis (TB). Methods: The demographic, clinical, radiological (X-ray and MRI) data of 105 patients with active spine TB were retrospectively analyzed. Patients were divided into two groups – with a neurological deficit (n = 52) as Group A and those without deficit (n = 53) as Group B. Univariate and multivariate logistic regression analysis was used to predict the risk factors for the neurological deficit. Results: The mean age of the patients was 38.1 years. The most common location of disease was dorsal region (35.2%). Paradiscal (77%) was the most common type of involvement. A statistically significant difference (p < 0.05) was noted in the location of disease, presence of cord compression, kyphosis, cord oedema, loss of CSF anterior to the cord, and degree of canal compromise or canal encroachment between two groups. Multivariate analysis revealed kyphosis > 30° (OR – 3.92, CI – 1.21–12.7, p – 0.023), canal encroachment > 50% (OR – 7.34, CI – 2.32–23.17, p – 0.001), and cord oedema (OR – 11.93, CI – 1.24–114.05, p – 0.03) as independent risk factors for predicting the risk of neurological deficit. Conclusion: Kyphosis > 30°, cord oedema, and canal encroachment (>50%) significantly predicted neurological deficit in patients with spine TB. Early surgery should be considered with all these risk factors to prevent a neurological deficit.https://www.sicot-j.org/articles/sicotj/full_html/2021/01/sicotj200148/sicotj200148.htmlspinal tuberculosispott’s paraplegianeurologic deficitrisk factors |
| spellingShingle | Mittal Samarth Yadav Gagandeep Ahuja Kaustubh Ifthekar Syed Sarkar Bhaskar Kandwal Pankaj Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control study SICOT-J spinal tuberculosis pott’s paraplegia neurologic deficit risk factors |
| title | Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control study |
| title_full | Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control study |
| title_fullStr | Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control study |
| title_full_unstemmed | Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control study |
| title_short | Predicting neurological deficit in patients with spinal tuberculosis – A single-center retrospective case-control study |
| title_sort | predicting neurological deficit in patients with spinal tuberculosis a single center retrospective case control study |
| topic | spinal tuberculosis pott’s paraplegia neurologic deficit risk factors |
| url | https://www.sicot-j.org/articles/sicotj/full_html/2021/01/sicotj200148/sicotj200148.html |
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