Targeting Tregs in Juvenile Idiopathic Arthritis and Juvenile Dermatomyositis—Insights From Other Diseases

Targeting Tregs in Juvenile Idiopathic Arthritis and Juvenile Dermatomyositis—Insights From Other Diseases

Regulatory T cells (Tregs) are believed to be dysfunctional in autoimmunity. Juvenile idiopathic arthritis (JIA) and juvenile dermatomyositis (JDM) result from a loss of normal immune regulation in specific tissues such as joints or muscle and skin, respectively. Here, we discuss recent findings in...

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Bibliographic Details
Main Authors: Romy E. Hoeppli, Anne M. Pesenacker
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
regulatory T cells
juvenile idiopathic arthritis
juvenile dermatomyositis
biomarker
therapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00046/full

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