Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible
Malignant Peripheral Nerve Sheath Tumor (MPNST) is biologically an aggressive tumor that is usually found in the extremities, trunk and infrequently found in the head and neck area particularly in the jaws, arising from the cells allied with nerve sheath. Mandibular MPNST may either arise from a p...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2016-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/8010/18263_CE(EK)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
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| author | Sumit Majumdar Sreekanth Kotina Nirujogi Mahesh Divya Uppala Singam Praveen Kumar |
| author_facet | Sumit Majumdar Sreekanth Kotina Nirujogi Mahesh Divya Uppala Singam Praveen Kumar |
| author_sort | Sumit Majumdar |
| collection | DOAJ |
| description | Malignant Peripheral Nerve Sheath Tumor (MPNST) is biologically an aggressive tumor that is usually found in the extremities, trunk and
infrequently found in the head and neck area particularly in the jaws, arising from the cells allied with nerve sheath. Mandibular MPNST
may either arise from a preexisting neurofibroma or develop de novo. Because of the greater variability from case to case in overall
appearance both clinically and histologically, a case of MPNST of the mandible in a 25-year-old female patient is reported. The lesion
was excised and immunohistological studies (S-100 & Neuron specific enolase) were conducted to confirm the neural origin. |
| first_indexed | 2024-12-12T04:46:19Z |
| format | Article |
| id | doaj.art-11eb7acfed7048afabb1f9806aa678fc |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-12T04:46:19Z |
| publishDate | 2016-06-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-11eb7acfed7048afabb1f9806aa678fc2022-12-22T00:37:37ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2016-06-01106ZD12ZD1310.7860/JCDR/2016/18263.8010Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in MandibleSumit Majumdar0Sreekanth Kotina1Nirujogi Mahesh2Divya Uppala3Singam Praveen Kumar4Professor and Head of Department, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Rushikonda, Visakhapatnam, India.Senior Lecturer, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Rushikonda, Visakhapatnam, India.Post Graduate Student, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Rushikonda, Visakhapatnam, India.Reader, Department of Oral pathology and Microbiology, GITAM Dental College and Hospital, Rushikonda, Visakhapatnam, India.Post Graduate Student, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital, Rushikonda, Visakhapatnam, India.Malignant Peripheral Nerve Sheath Tumor (MPNST) is biologically an aggressive tumor that is usually found in the extremities, trunk and infrequently found in the head and neck area particularly in the jaws, arising from the cells allied with nerve sheath. Mandibular MPNST may either arise from a preexisting neurofibroma or develop de novo. Because of the greater variability from case to case in overall appearance both clinically and histologically, a case of MPNST of the mandible in a 25-year-old female patient is reported. The lesion was excised and immunohistological studies (S-100 & Neuron specific enolase) were conducted to confirm the neural origin.https://jcdr.net/articles/PDF/8010/18263_CE(EK)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdfimmunohistochemistryneurofibrosarcomaneuron specific enolase |
| spellingShingle | Sumit Majumdar Sreekanth Kotina Nirujogi Mahesh Divya Uppala Singam Praveen Kumar Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible Journal of Clinical and Diagnostic Research immunohistochemistry neurofibrosarcoma neuron specific enolase |
| title | Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible |
| title_full | Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible |
| title_fullStr | Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible |
| title_full_unstemmed | Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible |
| title_short | Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible |
| title_sort | malignant peripheral nerve sheath tumor a rare malignancy in mandible |
| topic | immunohistochemistry neurofibrosarcoma neuron specific enolase |
| url | https://jcdr.net/articles/PDF/8010/18263_CE(EK)_F(AK)_PF1(EKAK)_PFA(AK)_PF2(PAG).pdf |
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