Application of Collagen-Based Hydrogel in Skin Wound Healing

The repair of skin injury has always been a concern in the medical field. As a kind of biopolymer material with a special network structure and function, collagen-based hydrogel has been widely used in the field of skin injury repair. In this paper, the current research and application status of pri...

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Main Authors: Yuan Zhang, Yong Wang, Ying Li, Yunpeng Yang, Mingyuan Jin, Xiaoying Lin, Zeming Zhuang, Kai Guo, Tao Zhang, Weiqiang Tan
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/9/3/185
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author Yuan Zhang
Yong Wang
Ying Li
Yunpeng Yang
Mingyuan Jin
Xiaoying Lin
Zeming Zhuang
Kai Guo
Tao Zhang
Weiqiang Tan
author_facet Yuan Zhang
Yong Wang
Ying Li
Yunpeng Yang
Mingyuan Jin
Xiaoying Lin
Zeming Zhuang
Kai Guo
Tao Zhang
Weiqiang Tan
author_sort Yuan Zhang
collection DOAJ
description The repair of skin injury has always been a concern in the medical field. As a kind of biopolymer material with a special network structure and function, collagen-based hydrogel has been widely used in the field of skin injury repair. In this paper, the current research and application status of primal hydrogels in the field of skin repair in recent years are comprehensively reviewed. Starting from the structure and properties of collagen, the preparation, structural properties, and application of collagen-based hydrogels in skin injury repair are emphatically described. Meanwhile, the influences of collagen types, preparation methods, and crosslinking methods on the structural properties of hydrogels are emphatically discussed. The future and development of collagen-based hydrogels are prospected, which is expected to provide reference for the research and application of collagen-based hydrogels for skin repair in the future.
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spelling doaj.art-11ee4bc4816b44308a6a4fbdd0a93d9e2023-11-17T11:14:27ZengMDPI AGGels2310-28612023-02-019318510.3390/gels9030185Application of Collagen-Based Hydrogel in Skin Wound HealingYuan Zhang0Yong Wang1Ying Li2Yunpeng Yang3Mingyuan Jin4Xiaoying Lin5Zeming Zhuang6Kai Guo7Tao Zhang8Weiqiang Tan9Department of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaDepartment of Plastic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3 East Qingchun Road, Hangzhou 310016, ChinaThe repair of skin injury has always been a concern in the medical field. As a kind of biopolymer material with a special network structure and function, collagen-based hydrogel has been widely used in the field of skin injury repair. In this paper, the current research and application status of primal hydrogels in the field of skin repair in recent years are comprehensively reviewed. Starting from the structure and properties of collagen, the preparation, structural properties, and application of collagen-based hydrogels in skin injury repair are emphatically described. Meanwhile, the influences of collagen types, preparation methods, and crosslinking methods on the structural properties of hydrogels are emphatically discussed. The future and development of collagen-based hydrogels are prospected, which is expected to provide reference for the research and application of collagen-based hydrogels for skin repair in the future.https://www.mdpi.com/2310-2861/9/3/185biopolymerswound healingcollagenskin repairhydrogels
spellingShingle Yuan Zhang
Yong Wang
Ying Li
Yunpeng Yang
Mingyuan Jin
Xiaoying Lin
Zeming Zhuang
Kai Guo
Tao Zhang
Weiqiang Tan
Application of Collagen-Based Hydrogel in Skin Wound Healing
Gels
biopolymers
wound healing
collagen
skin repair
hydrogels
title Application of Collagen-Based Hydrogel in Skin Wound Healing
title_full Application of Collagen-Based Hydrogel in Skin Wound Healing
title_fullStr Application of Collagen-Based Hydrogel in Skin Wound Healing
title_full_unstemmed Application of Collagen-Based Hydrogel in Skin Wound Healing
title_short Application of Collagen-Based Hydrogel in Skin Wound Healing
title_sort application of collagen based hydrogel in skin wound healing
topic biopolymers
wound healing
collagen
skin repair
hydrogels
url https://www.mdpi.com/2310-2861/9/3/185
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