Optimized Dosing Regimens of Meropenem in Septic Children Receiving Extracorporeal Life Support
Objectives: To develop a population pharmacokinetic model of meropenem in children with sepsis receiving extracorporeal life support (ECLS) and optimize the dosage regimen based on investigating the probability of target attainment (PTA).Methods: The children with sepsis were prospectively enrolled...
Main Authors: | Yixue Wang, Weiming Chen, Yidie Huang, Guangfei Wang, Zhiping Li, Gangfeng Yan, Chao Chen, Guoping Lu |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2021-08-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2021.699191/full |
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