Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective study
Abstract Objective The aim of this study was to determine the antimicrobial resistance pattern of bacterial isolates from different specimens at various hospitals and private diagnostic service laboratories in Ghana. Results A retrospective data of culture and sensitivity test results from 2016 were...
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| Language: | English |
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BMC
2018-04-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-018-3377-7 |
| _version_ | 1811197302022340608 |
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| author | Jibril Mohammed Yaovi Mahuton Gildas Hounmanou Line Elnif Thomsen |
| author_facet | Jibril Mohammed Yaovi Mahuton Gildas Hounmanou Line Elnif Thomsen |
| author_sort | Jibril Mohammed |
| collection | DOAJ |
| description | Abstract Objective The aim of this study was to determine the antimicrobial resistance pattern of bacterial isolates from different specimens at various hospitals and private diagnostic service laboratories in Ghana. Results A retrospective data of culture and sensitivity test results from 2016 were extracted from the microbiology record book of six laboratories in Accra, Ghana. The data included type of clinical specimen, sex of patient, name of bacterial isolate and antibiotic resistance profile. A total of 16.6% (n = 10,237) resistant isolates were obtained, however, the proportions of resistant isolates varied significantly between laboratories. High resistance towards tetracycline, ampicillin, cotrimoxazole and cephalosporins, but low towards amoxiclav and aminoglycosides, was observed. This study identified E. coli and Staphylococcus species as the major resistant bacteria from clinical specimen in Accra and the highest prevalence of the isolates was found in urine specimens in all six laboratories (69.1%, n = 204; 52.6%, n = 36; 52.3%, n = 350; 37.9%, n = 298; 53%, n = 219; 62.1%, n = 594) and in female patients (81.4, 50 and 69.5%). Regular surveillance and local susceptibility pattern analysis is extremely important in selecting the most appropriate and effective antibiotic for the treatment of bacterial infections. |
| first_indexed | 2024-04-12T01:12:55Z |
| format | Article |
| id | doaj.art-11f1c42c99534c098c99359ddf0ee6c2 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-04-12T01:12:55Z |
| publishDate | 2018-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-11f1c42c99534c098c99359ddf0ee6c22022-12-22T03:54:03ZengBMCBMC Research Notes1756-05002018-04-011111610.1186/s13104-018-3377-7Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective studyJibril Mohammed0Yaovi Mahuton Gildas Hounmanou1Line Elnif Thomsen2Department of Microbiology, Parasitology and Biotechnology, College of Veterinary Medicine and Biomedical Sciences, Sokoine University of AgricultureDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of CopenhagenAbstract Objective The aim of this study was to determine the antimicrobial resistance pattern of bacterial isolates from different specimens at various hospitals and private diagnostic service laboratories in Ghana. Results A retrospective data of culture and sensitivity test results from 2016 were extracted from the microbiology record book of six laboratories in Accra, Ghana. The data included type of clinical specimen, sex of patient, name of bacterial isolate and antibiotic resistance profile. A total of 16.6% (n = 10,237) resistant isolates were obtained, however, the proportions of resistant isolates varied significantly between laboratories. High resistance towards tetracycline, ampicillin, cotrimoxazole and cephalosporins, but low towards amoxiclav and aminoglycosides, was observed. This study identified E. coli and Staphylococcus species as the major resistant bacteria from clinical specimen in Accra and the highest prevalence of the isolates was found in urine specimens in all six laboratories (69.1%, n = 204; 52.6%, n = 36; 52.3%, n = 350; 37.9%, n = 298; 53%, n = 219; 62.1%, n = 594) and in female patients (81.4, 50 and 69.5%). Regular surveillance and local susceptibility pattern analysis is extremely important in selecting the most appropriate and effective antibiotic for the treatment of bacterial infections.http://link.springer.com/article/10.1186/s13104-018-3377-7Antimicrobial resistanceClinical bacteriaGhana |
| spellingShingle | Jibril Mohammed Yaovi Mahuton Gildas Hounmanou Line Elnif Thomsen Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective study BMC Research Notes Antimicrobial resistance Clinical bacteria Ghana |
| title | Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective study |
| title_full | Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective study |
| title_fullStr | Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective study |
| title_full_unstemmed | Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective study |
| title_short | Antimicrobial resistance among clinically relevant bacterial isolates in Accra: a retrospective study |
| title_sort | antimicrobial resistance among clinically relevant bacterial isolates in accra a retrospective study |
| topic | Antimicrobial resistance Clinical bacteria Ghana |
| url | http://link.springer.com/article/10.1186/s13104-018-3377-7 |
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