Heat Shock proteins expression in different types of classical Hodgkin`s Lymphoma
In the study estimation of heat shock proteins hsp60 and hsp90 expression in tumor tissue were conducted in lymphocyte rich, mixed cellularity and ymphocyte depleted (reticular type) variants of classical Hodgkins lymphoma. It was shown that HRS-cells and cellular microenvironment in the studied tum...
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Format: | Article |
Language: | Russian |
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Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy
2013-01-01
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Series: | Морфологія |
Subjects: | |
Online Access: | http://www.morphology.dp.ua/_pub/MORPHO-2013-07-01/13tvoklc.pdf |
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author | Tumanskiy V.O. Shavrin V.O. |
author_facet | Tumanskiy V.O. Shavrin V.O. |
author_sort | Tumanskiy V.O. |
collection | DOAJ |
description | In the study estimation of heat shock proteins hsp60 and hsp90 expression in tumor tissue were conducted in lymphocyte rich, mixed cellularity and ymphocyte depleted (reticular type) variants of classical Hodgkins lymphoma. It was shown that HRS-cells and cellular microenvironment in the studied tumor tissues have in their cytoplasm heat shock proteins, what may cause resistance to inner and outer damage effects. Expression increases from lymphocyte rich to mixed cellularity and the most significant in tumor tissue of Hodgkin`s sarcoma. |
first_indexed | 2024-12-21T09:50:46Z |
format | Article |
id | doaj.art-11f38b73fdfb456a88c20a5aca17818c |
institution | Directory Open Access Journal |
issn | 1997-9665 |
language | Russian |
last_indexed | 2024-12-21T09:50:46Z |
publishDate | 2013-01-01 |
publisher | Ministry of Health of Ukraine. Dnipropetrovsk Medical Academy |
record_format | Article |
series | Морфологія |
spelling | doaj.art-11f38b73fdfb456a88c20a5aca17818c2022-12-21T19:08:12ZrusMinistry of Health of Ukraine. Dnipropetrovsk Medical AcademyМорфологія1997-96652013-01-01717881Heat Shock proteins expression in different types of classical Hodgkin`s LymphomaTumanskiy V.O.Shavrin V.O.In the study estimation of heat shock proteins hsp60 and hsp90 expression in tumor tissue were conducted in lymphocyte rich, mixed cellularity and ymphocyte depleted (reticular type) variants of classical Hodgkins lymphoma. It was shown that HRS-cells and cellular microenvironment in the studied tumor tissues have in their cytoplasm heat shock proteins, what may cause resistance to inner and outer damage effects. Expression increases from lymphocyte rich to mixed cellularity and the most significant in tumor tissue of Hodgkin`s sarcoma.http://www.morphology.dp.ua/_pub/MORPHO-2013-07-01/13tvoklc.pdfHodgkin`s lymphomaHRS-cellsheat shock proteins |
spellingShingle | Tumanskiy V.O. Shavrin V.O. Heat Shock proteins expression in different types of classical Hodgkin`s Lymphoma Морфологія Hodgkin`s lymphoma HRS-cells heat shock proteins |
title | Heat Shock proteins expression in different types of classical Hodgkin`s Lymphoma |
title_full | Heat Shock proteins expression in different types of classical Hodgkin`s Lymphoma |
title_fullStr | Heat Shock proteins expression in different types of classical Hodgkin`s Lymphoma |
title_full_unstemmed | Heat Shock proteins expression in different types of classical Hodgkin`s Lymphoma |
title_short | Heat Shock proteins expression in different types of classical Hodgkin`s Lymphoma |
title_sort | heat shock proteins expression in different types of classical hodgkin s lymphoma |
topic | Hodgkin`s lymphoma HRS-cells heat shock proteins |
url | http://www.morphology.dp.ua/_pub/MORPHO-2013-07-01/13tvoklc.pdf |
work_keys_str_mv | AT tumanskiyvo heatshockproteinsexpressionindifferenttypesofclassicalhodgkinslymphoma AT shavrinvo heatshockproteinsexpressionindifferenttypesofclassicalhodgkinslymphoma |