T vector velocity: A new ECG biomarker for identifying drug effects on cardiac ventricular repolarization.
<h4>Background</h4>We present a new family of ECG biomarkers for assessing drug effects on ventricular repolarization. We show that drugs blocking inward (depolarizing) ion currents cause a relative increase of the T vector velocity (TVV) and accelerate repolarization, while drugs blocki...
Main Authors: | Werner Bystricky, Christoph Maier, Gary Gintant, Dennis Bergau, Kent Kamradt, Patrick Welsh, David Carter |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0204712 |
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