| Summary: | A new compound (<i>E</i>)-3-[3-(4-morpholinophenyl)acryloyl]-2<i>H</i>-chromen-2-one, a coumarin based chalcone derivative, has been successfully synthesized employing a molecular hybridization method through the reaction between 3-acetylcoumarin and 4-morpholinobenzaldehyde using a Claisen–Schmidt reaction using <i>p</i>TSA as a catalyst. The structure of the title compound was established using spectroscopic data FTIR, HRESI-MS, <sup>1</sup>H- and <sup>13</sup>C-NMR. The anticancer activity against breast cancer cells line T47D and cervix cancer cells line HeLa was determined using an MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay.
|
|---|