Increased temporal stride variability contributes to impaired gait coordination after stroke
Abstract Heightened motor variability is a prominent impairment after stroke. During walking, stroke survivors show increased spatial and temporal variability; however, the functional implications of increased gait variability are not well understood. Here, we determine the effect of gait variabilit...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-17017-1 |
| _version_ | 1818163047346208768 |
|---|---|
| author | Prakruti Patel Diana Enzastiga Agostina Casamento-Moran Evangelos A. Christou Neha Lodha |
| author_facet | Prakruti Patel Diana Enzastiga Agostina Casamento-Moran Evangelos A. Christou Neha Lodha |
| author_sort | Prakruti Patel |
| collection | DOAJ |
| description | Abstract Heightened motor variability is a prominent impairment after stroke. During walking, stroke survivors show increased spatial and temporal variability; however, the functional implications of increased gait variability are not well understood. Here, we determine the effect of gait variability on the coordination between lower limbs during overground walking in stroke survivors. Ambulatory stroke survivors and controls walked at a preferred pace. We measured stride length and stride time variability, and accuracy and consistency of anti-phase gait coordination with phase coordination index (PCI). Stroke survivors showed increased stride length variability, stride time variability, and PCI compared with controls. Stride time variability but not stride length variability predicted 43% of the variance in PCI in the stroke group. Stride time variability emerged as a significant predictor of error and consistency of phase. Despite impaired spatial and temporal gait variability following stroke, increased temporal variability contributes to disrupted accuracy and consistency of gait coordination. We provide novel evidence that decline in gait coordination after stroke is associated with exacerbated stride time variability, but not stride length variability. Temporal gait variability may be a robust indicator of the decline in locomotor function and an ideal target for motor interventions that promote stable walking after stroke. |
| first_indexed | 2024-12-11T16:43:21Z |
| format | Article |
| id | doaj.art-11f842fe3ab94f3d90c1afbc433154e0 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-11T16:43:21Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-11f842fe3ab94f3d90c1afbc433154e02022-12-22T00:58:16ZengNature PortfolioScientific Reports2045-23222022-07-0112111010.1038/s41598-022-17017-1Increased temporal stride variability contributes to impaired gait coordination after strokePrakruti Patel0Diana Enzastiga1Agostina Casamento-Moran2Evangelos A. Christou3Neha Lodha4Movement Neuroscience and Rehabilitation Laboratory, Department of Health and Exercise Science, Colorado State UniversityMovement Neuroscience and Rehabilitation Laboratory, Department of Health and Exercise Science, Colorado State UniversityDepartment of Applied Physiology and Kinesiology, University of FloridaDepartment of Applied Physiology and Kinesiology, University of FloridaMovement Neuroscience and Rehabilitation Laboratory, Department of Health and Exercise Science, Colorado State UniversityAbstract Heightened motor variability is a prominent impairment after stroke. During walking, stroke survivors show increased spatial and temporal variability; however, the functional implications of increased gait variability are not well understood. Here, we determine the effect of gait variability on the coordination between lower limbs during overground walking in stroke survivors. Ambulatory stroke survivors and controls walked at a preferred pace. We measured stride length and stride time variability, and accuracy and consistency of anti-phase gait coordination with phase coordination index (PCI). Stroke survivors showed increased stride length variability, stride time variability, and PCI compared with controls. Stride time variability but not stride length variability predicted 43% of the variance in PCI in the stroke group. Stride time variability emerged as a significant predictor of error and consistency of phase. Despite impaired spatial and temporal gait variability following stroke, increased temporal variability contributes to disrupted accuracy and consistency of gait coordination. We provide novel evidence that decline in gait coordination after stroke is associated with exacerbated stride time variability, but not stride length variability. Temporal gait variability may be a robust indicator of the decline in locomotor function and an ideal target for motor interventions that promote stable walking after stroke.https://doi.org/10.1038/s41598-022-17017-1 |
| spellingShingle | Prakruti Patel Diana Enzastiga Agostina Casamento-Moran Evangelos A. Christou Neha Lodha Increased temporal stride variability contributes to impaired gait coordination after stroke Scientific Reports |
| title | Increased temporal stride variability contributes to impaired gait coordination after stroke |
| title_full | Increased temporal stride variability contributes to impaired gait coordination after stroke |
| title_fullStr | Increased temporal stride variability contributes to impaired gait coordination after stroke |
| title_full_unstemmed | Increased temporal stride variability contributes to impaired gait coordination after stroke |
| title_short | Increased temporal stride variability contributes to impaired gait coordination after stroke |
| title_sort | increased temporal stride variability contributes to impaired gait coordination after stroke |
| url | https://doi.org/10.1038/s41598-022-17017-1 |
| work_keys_str_mv | AT prakrutipatel increasedtemporalstridevariabilitycontributestoimpairedgaitcoordinationafterstroke AT dianaenzastiga increasedtemporalstridevariabilitycontributestoimpairedgaitcoordinationafterstroke AT agostinacasamentomoran increasedtemporalstridevariabilitycontributestoimpairedgaitcoordinationafterstroke AT evangelosachristou increasedtemporalstridevariabilitycontributestoimpairedgaitcoordinationafterstroke AT nehalodha increasedtemporalstridevariabilitycontributestoimpairedgaitcoordinationafterstroke |