Molecular Mechanisms of KDELC2 on Glioblastoma Tumorigenesis and Temozolomide Resistance

Molecular Mechanisms of KDELC2 on Glioblastoma Tumorigenesis and Temozolomide Resistance

The activation of the Notch pathway induces glioblastoma (GBM) development. Since KDEL (Lys-Asp-Glu-Leu) containing 2 (KDELC2) is involved in the Notch pathway, the detailed mechanism is still undetermined. The Cancer Genome Atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) databases revealed that...

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Bibliographic Details
Main Authors: Yu-Ling Tsai, Hsin-Han Chang, Ying-Chuan Chen, Yu-Chan Chang, Ying Chen, Wen-Chiuan Tsai
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Biomedicines
Subjects:
KDELC2
glioblastoma
Notch
temozolomide
Online Access:https://www.mdpi.com/2227-9059/8/9/339

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