Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants
The gut microbiome is closely related to host nutrition and health. However, the relationships between gut microorganisms and host lifestyle are not well characterized. In the absence of confounding geographic variation, we defined clear patterns of variation in the gut microbiomes of Asian elephant...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-02-01
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| Series: | Genomics, Proteomics & Bioinformatics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1672022923000694 |
| _version_ | 1797328432048111616 |
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| author | Chengbo Zhang Zhenghan Lian Bo Xu Qingzhong Shen Mingwei Bao Zunxi Huang Hongchen Jiang Wenjun Li |
| author_facet | Chengbo Zhang Zhenghan Lian Bo Xu Qingzhong Shen Mingwei Bao Zunxi Huang Hongchen Jiang Wenjun Li |
| author_sort | Chengbo Zhang |
| collection | DOAJ |
| description | The gut microbiome is closely related to host nutrition and health. However, the relationships between gut microorganisms and host lifestyle are not well characterized. In the absence of confounding geographic variation, we defined clear patterns of variation in the gut microbiomes of Asian elephants (AEs) in the Wild Elephant Valley, Xishuangbanna, China, along a lifestyle gradient (completely captive, semicaptive, semiwild, and completely wild). A phylogenetic analysis using the 16S rRNA gene sequences highlighted that the microbial diversity decreased as the degree of captivity increased. Furthermore, the results showed that the bacterial taxon WCHB1-41_c was substantially affected by lifestyle variations. qRT-PCR analysis revealed a paucity of genes related to butyrate production in the gut microbiome of AEs with a completely wild lifestyle, which may be due to the increased unfavorable environmental factors. Overall, these results demonstrate the distinct gut microbiome characteristics among AEs with a gradient of lifestyles and provide a basis for designing strategies to improve the well-being or conservation of this important animal species. |
| first_indexed | 2024-03-08T06:51:43Z |
| format | Article |
| id | doaj.art-11fe15002b8f47cda139fc1014d750e7 |
| institution | Directory Open Access Journal |
| issn | 1672-0229 |
| language | English |
| last_indexed | 2024-03-08T06:51:43Z |
| publishDate | 2023-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Genomics, Proteomics & Bioinformatics |
| spelling | doaj.art-11fe15002b8f47cda139fc1014d750e72024-02-03T06:46:59ZengElsevierGenomics, Proteomics & Bioinformatics1672-02292023-02-01211150163Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian ElephantsChengbo Zhang0Zhenghan Lian1Bo Xu2Qingzhong Shen3Mingwei Bao4Zunxi Huang5Hongchen Jiang6Wenjun Li7Engineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, School of Life Sciences, Yunnan Normal University, Kunming 650500, ChinaState Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, ChinaEngineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, School of Life Sciences, Yunnan Normal University, Kunming 650500, ChinaXishuangbanna National Nature Reserve Management and Protection Bureau, Jinghong 666100, ChinaAsian Elephant Provenance Breeding and Rescue Center in Xishuangbanna, Jinghong 666100, ChinaEngineering Research Center of Sustainable Development and Utilization of Biomass Energy, Ministry of Education, School of Life Sciences, Yunnan Normal University, Kunming 650500, China; Corresponding authors.State Key Laboratory of Biogeology and Environmental Geology, China University of Geosciences, Wuhan 430074, China; Corresponding authors.State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory of Plant Resources and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China; Corresponding authors.The gut microbiome is closely related to host nutrition and health. However, the relationships between gut microorganisms and host lifestyle are not well characterized. In the absence of confounding geographic variation, we defined clear patterns of variation in the gut microbiomes of Asian elephants (AEs) in the Wild Elephant Valley, Xishuangbanna, China, along a lifestyle gradient (completely captive, semicaptive, semiwild, and completely wild). A phylogenetic analysis using the 16S rRNA gene sequences highlighted that the microbial diversity decreased as the degree of captivity increased. Furthermore, the results showed that the bacterial taxon WCHB1-41_c was substantially affected by lifestyle variations. qRT-PCR analysis revealed a paucity of genes related to butyrate production in the gut microbiome of AEs with a completely wild lifestyle, which may be due to the increased unfavorable environmental factors. Overall, these results demonstrate the distinct gut microbiome characteristics among AEs with a gradient of lifestyles and provide a basis for designing strategies to improve the well-being or conservation of this important animal species.http://www.sciencedirect.com/science/article/pii/S1672022923000694Asian elephantGut microbiomePhylogenetic analysisLifestyleHost health |
| spellingShingle | Chengbo Zhang Zhenghan Lian Bo Xu Qingzhong Shen Mingwei Bao Zunxi Huang Hongchen Jiang Wenjun Li Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants Genomics, Proteomics & Bioinformatics Asian elephant Gut microbiome Phylogenetic analysis Lifestyle Host health |
| title | Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants |
| title_full | Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants |
| title_fullStr | Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants |
| title_full_unstemmed | Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants |
| title_short | Gut Microbiome Variation Along A Lifestyle Gradient Reveals Threats Faced by Asian Elephants |
| title_sort | gut microbiome variation along a lifestyle gradient reveals threats faced by asian elephants |
| topic | Asian elephant Gut microbiome Phylogenetic analysis Lifestyle Host health |
| url | http://www.sciencedirect.com/science/article/pii/S1672022923000694 |
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