Effect of Polyphenols Intake on Obesity-Induced Maternal Programming
Excess caloric intake and body fat accumulation lead to obesity, a complex chronic disease that represents a significant public health problem due to the health-related risk factors. There is growing evidence showing that maternal obesity can program the offspring, which influences neonatal phenotyp...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-07-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/13/7/2390 |
| _version_ | 1797526364936470528 |
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| author | Isabela Monique Fortunato Tanila Wood dos Santos Lucio Fábio Caldas Ferraz Juliana Carvalho Santos Marcelo Lima Ribeiro |
| author_facet | Isabela Monique Fortunato Tanila Wood dos Santos Lucio Fábio Caldas Ferraz Juliana Carvalho Santos Marcelo Lima Ribeiro |
| author_sort | Isabela Monique Fortunato |
| collection | DOAJ |
| description | Excess caloric intake and body fat accumulation lead to obesity, a complex chronic disease that represents a significant public health problem due to the health-related risk factors. There is growing evidence showing that maternal obesity can program the offspring, which influences neonatal phenotype and predispose offspring to metabolic disorders such as obesity. This increased risk may also be epigenetically transmitted across generations. Thus, there is an imperative need to find effective reprogramming approaches in order to resume normal fetal development. Polyphenols are bioactive compounds found in vegetables and fruits that exert its anti-obesity effect through its powerful anti-oxidant and anti-inflammatory activities. Polyphenol supplementation has been proven to counteract the prejudicial effects of maternal obesity programming on progeny. Indeed, some polyphenols can cross the placenta and protect the fetal predisposition against obesity. The present review summarizes the effects of dietary polyphenols on obesity-induced maternal reprogramming as an offspring anti-obesity approach. |
| first_indexed | 2024-03-10T09:29:12Z |
| format | Article |
| id | doaj.art-12025e3697464bd49f210f7fbb48b248 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-10T09:29:12Z |
| publishDate | 2021-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-12025e3697464bd49f210f7fbb48b2482023-11-22T04:36:45ZengMDPI AGNutrients2072-66432021-07-01137239010.3390/nu13072390Effect of Polyphenols Intake on Obesity-Induced Maternal ProgrammingIsabela Monique Fortunato0Tanila Wood dos Santos1Lucio Fábio Caldas Ferraz2Juliana Carvalho Santos3Marcelo Lima Ribeiro4Post Graduate Program in Health Science, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, BrazilPost Graduate Program in Health Science, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, BrazilPost Graduate Program in Health Science, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, BrazilLymphoma Translational Group, Josep Carreras Leukemia Research Institute (IJC), 08916 Badalona, SpainPost Graduate Program in Health Science, Universidade São Francisco (USF), Bragança Paulista 12916-900, SP, BrazilExcess caloric intake and body fat accumulation lead to obesity, a complex chronic disease that represents a significant public health problem due to the health-related risk factors. There is growing evidence showing that maternal obesity can program the offspring, which influences neonatal phenotype and predispose offspring to metabolic disorders such as obesity. This increased risk may also be epigenetically transmitted across generations. Thus, there is an imperative need to find effective reprogramming approaches in order to resume normal fetal development. Polyphenols are bioactive compounds found in vegetables and fruits that exert its anti-obesity effect through its powerful anti-oxidant and anti-inflammatory activities. Polyphenol supplementation has been proven to counteract the prejudicial effects of maternal obesity programming on progeny. Indeed, some polyphenols can cross the placenta and protect the fetal predisposition against obesity. The present review summarizes the effects of dietary polyphenols on obesity-induced maternal reprogramming as an offspring anti-obesity approach.https://www.mdpi.com/2072-6643/13/7/2390bioactive compoundsnutraceuticalmaternal obesityadipose tissuemetabolic disorders |
| spellingShingle | Isabela Monique Fortunato Tanila Wood dos Santos Lucio Fábio Caldas Ferraz Juliana Carvalho Santos Marcelo Lima Ribeiro Effect of Polyphenols Intake on Obesity-Induced Maternal Programming Nutrients bioactive compounds nutraceutical maternal obesity adipose tissue metabolic disorders |
| title | Effect of Polyphenols Intake on Obesity-Induced Maternal Programming |
| title_full | Effect of Polyphenols Intake on Obesity-Induced Maternal Programming |
| title_fullStr | Effect of Polyphenols Intake on Obesity-Induced Maternal Programming |
| title_full_unstemmed | Effect of Polyphenols Intake on Obesity-Induced Maternal Programming |
| title_short | Effect of Polyphenols Intake on Obesity-Induced Maternal Programming |
| title_sort | effect of polyphenols intake on obesity induced maternal programming |
| topic | bioactive compounds nutraceutical maternal obesity adipose tissue metabolic disorders |
| url | https://www.mdpi.com/2072-6643/13/7/2390 |
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