Hippocampal circuit dysfunction in psychosis

Abstract Despite strong evidence of the neurodevelopmental origins of psychosis, current pharmacological treatment is not usually initiated until after a clinical diagnosis is made, and is focussed on antagonising striatal dopamine receptors. These drugs are only partially effective, have serious si...

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Bibliographic Details
Main Authors: Samuel Knight, Robert McCutcheon, Daniella Dwir, Anthony A. Grace, Owen O’Daly, Philip McGuire, Gemma Modinos
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-022-02115-5

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