Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring

Diabetes, a chronic, metabolic disease characterized by elevated levels of blood glucose, over time leads to serious damage to the blood vessels, nerves, eyes, kidneys, and heart. Diabetes affects 422 million people globally, with the majority residing in low- and middle-income nations, and approxim...

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Main Authors: Anthony Ko, Caizhi Liao
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Hybrid Advances
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2773207X23000350
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author Anthony Ko
Caizhi Liao
author_facet Anthony Ko
Caizhi Liao
author_sort Anthony Ko
collection DOAJ
description Diabetes, a chronic, metabolic disease characterized by elevated levels of blood glucose, over time leads to serious damage to the blood vessels, nerves, eyes, kidneys, and heart. Diabetes affects 422 million people globally, with the majority residing in low- and middle-income nations, and approximately 1.5 million deaths are directly attributed to diabetes annually. Thus, detecting diabetes early is crucial to prevent, monitor, or postpone the advancement of the disease and its associated complications. However, current blood glucose tests for diabetic patients have a significant drawback in that these methods require frequent intrusive blood sampling. Promisingly, salivary analysis has emerged as a non-invasive and convenient alternative glucose monitoring approach for diabetics. In this review, we attempt to chart the landscape of the emerging field of salivary glucose analysis. It is not our intention to wholly review all related work, but rather an assorted selection of seminar reports that exemplify the development trajectory of burgeoning salivary glucose measurement (SGM). The fundamental advantageous nature of SGM as a novel non-invasive method in SGM diagnostic and monitoring fields will be thematically and thoroughly discussed. To inspire next-stage clinical transitional development of this fruitful field, we then explicate challenges that remain to be addressed, and present future directions of salivary glucose analysis.
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spelling doaj.art-12079afe29a940eea73f9fe2947aa3b02023-08-21T04:20:51ZengElsevierHybrid Advances2773-207X2023-08-013100052Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoringAnthony Ko0Caizhi Liao1Renaissance Bio, New Territories, Hong Kong SAR, ChinaRenaissance Bio, New Territories, Hong Kong SAR, China; QIMR Berghofer Medical Research Institute, Herston QLD, 4006, Brisbane, Australia; Corresponding author. QIMR Berghofer Medical Research Institute & Renaissance Bio, China.Diabetes, a chronic, metabolic disease characterized by elevated levels of blood glucose, over time leads to serious damage to the blood vessels, nerves, eyes, kidneys, and heart. Diabetes affects 422 million people globally, with the majority residing in low- and middle-income nations, and approximately 1.5 million deaths are directly attributed to diabetes annually. Thus, detecting diabetes early is crucial to prevent, monitor, or postpone the advancement of the disease and its associated complications. However, current blood glucose tests for diabetic patients have a significant drawback in that these methods require frequent intrusive blood sampling. Promisingly, salivary analysis has emerged as a non-invasive and convenient alternative glucose monitoring approach for diabetics. In this review, we attempt to chart the landscape of the emerging field of salivary glucose analysis. It is not our intention to wholly review all related work, but rather an assorted selection of seminar reports that exemplify the development trajectory of burgeoning salivary glucose measurement (SGM). The fundamental advantageous nature of SGM as a novel non-invasive method in SGM diagnostic and monitoring fields will be thematically and thoroughly discussed. To inspire next-stage clinical transitional development of this fruitful field, we then explicate challenges that remain to be addressed, and present future directions of salivary glucose analysis.http://www.sciencedirect.com/science/article/pii/S2773207X23000350DiabetesGlucose analysisNon-invasiveSalivary glucose measurementSalivary analysis
spellingShingle Anthony Ko
Caizhi Liao
Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring
Hybrid Advances
Diabetes
Glucose analysis
Non-invasive
Salivary glucose measurement
Salivary analysis
title Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring
title_full Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring
title_fullStr Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring
title_full_unstemmed Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring
title_short Salivary glucose measurement: A holy ground for next generation of non-invasive diabetic monitoring
title_sort salivary glucose measurement a holy ground for next generation of non invasive diabetic monitoring
topic Diabetes
Glucose analysis
Non-invasive
Salivary glucose measurement
Salivary analysis
url http://www.sciencedirect.com/science/article/pii/S2773207X23000350
work_keys_str_mv AT anthonyko salivaryglucosemeasurementaholygroundfornextgenerationofnoninvasivediabeticmonitoring
AT caizhiliao salivaryglucosemeasurementaholygroundfornextgenerationofnoninvasivediabeticmonitoring