Mucoadhesive drug delivery system: An overview
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tra...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | Journal of Advanced Pharmaceutical Technology & Research |
| Subjects: | |
| Online Access: | http://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=4;spage=381;epage=387;aulast=Boddupalli |
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| author | Bindu M Boddupalli Zulkar N.K Mohammed Ravinder A Nath David Banji |
| author_facet | Bindu M Boddupalli Zulkar N.K Mohammed Ravinder A Nath David Banji |
| author_sort | Bindu M Boddupalli |
| collection | DOAJ |
| description | Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, factors influencing the mucoadhesive devices and also various mucoadhesive dosage forms. |
| first_indexed | 2024-12-21T22:12:30Z |
| format | Article |
| id | doaj.art-120967f43c64422fab29cb765d7b7e4e |
| institution | Directory Open Access Journal |
| issn | 2231-4040 0976-2094 |
| language | English |
| last_indexed | 2024-12-21T22:12:30Z |
| publishDate | 2010-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Advanced Pharmaceutical Technology & Research |
| spelling | doaj.art-120967f43c64422fab29cb765d7b7e4e2022-12-21T18:48:32ZengWolters Kluwer Medknow PublicationsJournal of Advanced Pharmaceutical Technology & Research2231-40400976-20942010-01-011438138710.4103/0110-5558.76436Mucoadhesive drug delivery system: An overviewBindu M BoddupalliZulkar N.K MohammedRavinder A NathDavid BanjiMucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, factors influencing the mucoadhesive devices and also various mucoadhesive dosage forms.http://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=4;spage=381;epage=387;aulast=BoddupalliMucoadhesiontheoriesmucoadhesive dosage forms |
| spellingShingle | Bindu M Boddupalli Zulkar N.K Mohammed Ravinder A Nath David Banji Mucoadhesive drug delivery system: An overview Journal of Advanced Pharmaceutical Technology & Research Mucoadhesion theories mucoadhesive dosage forms |
| title | Mucoadhesive drug delivery system: An overview |
| title_full | Mucoadhesive drug delivery system: An overview |
| title_fullStr | Mucoadhesive drug delivery system: An overview |
| title_full_unstemmed | Mucoadhesive drug delivery system: An overview |
| title_short | Mucoadhesive drug delivery system: An overview |
| title_sort | mucoadhesive drug delivery system an overview |
| topic | Mucoadhesion theories mucoadhesive dosage forms |
| url | http://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=4;spage=381;epage=387;aulast=Boddupalli |
| work_keys_str_mv | AT bindumboddupalli mucoadhesivedrugdeliverysystemanoverview AT zulkarnkmohammed mucoadhesivedrugdeliverysystemanoverview AT ravinderanath mucoadhesivedrugdeliverysystemanoverview AT davidbanji mucoadhesivedrugdeliverysystemanoverview |