Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size
Shear wave elastography (SWE) is a type of ultrasound elastography with which the elastic properties of breast tissues can be quantitatively assessed. The purpose of this study was to determine the impact of different regions of interest (ROI) and lesion size on the performance of SWE in differentia...
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MDPI AG
2021-06-01
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| Online Access: | https://www.mdpi.com/2075-4418/11/6/1015 |
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| author | Antonio Bulum Gordana Ivanac Eugen Divjak Iva Biondić Špoljar Martina Džoić Dominković Kristina Bojanić Marko Lucijanić Boris Brkljačić |
| author_facet | Antonio Bulum Gordana Ivanac Eugen Divjak Iva Biondić Špoljar Martina Džoić Dominković Kristina Bojanić Marko Lucijanić Boris Brkljačić |
| author_sort | Antonio Bulum |
| collection | DOAJ |
| description | Shear wave elastography (SWE) is a type of ultrasound elastography with which the elastic properties of breast tissues can be quantitatively assessed. The purpose of this study was to determine the impact of different regions of interest (ROI) and lesion size on the performance of SWE in differentiating malignant breast lesions. The study included 150 female patients with histopathologically confirmed malignant breast lesions. Minimal (E<sub>min</sub>), mean (E<sub>mean</sub>), maximal (E<sub>max</sub>) elastic modulus and elasticity ratio (e-ratio) values were measured using a circular ROI size of 2, 4 and 6 mm diameters and the lesions were divided into large (diameter ≥ 15 mm) and small (diameter < 15 mm). Highest E<sub>min</sub>, E<sub>mean</sub> and e-ratio values and lowest variability were observed when using the 2 mm ROI. E<sub>max</sub> values did not differ between different ROI sizes. Larger lesions had significantly higher E<sub>mean</sub> and E<sub>max</sub> values, but there was no difference in e-ratio values between lesions of different sizes. In conclusion, when measuring the E<sub>min</sub>, E<sub>mean</sub> and e-ratio of malignant breast lesions using SWE the smallest possible ROI size should be used regardless of lesion size. ROI size has no impact on E<sub>max</sub> values while lesion size has no impact on e-ratio values. |
| first_indexed | 2024-03-10T10:47:31Z |
| format | Article |
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| language | English |
| last_indexed | 2024-03-10T10:47:31Z |
| publishDate | 2021-06-01 |
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| series | Diagnostics |
| spelling | doaj.art-120bc22c5a334640b93259f069d514582023-11-21T22:27:45ZengMDPI AGDiagnostics2075-44182021-06-01116101510.3390/diagnostics11061015Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion SizeAntonio Bulum0Gordana Ivanac1Eugen Divjak2Iva Biondić Špoljar3Martina Džoić Dominković4Kristina Bojanić5Marko Lucijanić6Boris Brkljačić7Department of Diagnostic and Interventional Radiology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, CroatiaDepartment of Diagnostic and Interventional Radiology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, CroatiaDepartment of Diagnostic and Interventional Radiology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, CroatiaDepartment of Diagnostic and Interventional Radiology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, CroatiaDepartment of Radiology, General Hospital Orašje, 3rd Street, 76270 Orašje, Bosnia and HerzegovinaDepartment of Otorhinolaryngology, Neurosurgery and Radiology, Faculty of Dental Medicine and Health Osijek, J.J. Strossmayer University of Osijek, Crkvena ul. 21, 31000 Osijek, CroatiaDepartment of Radiology, School of Medicine, University of Zagreb, Šalata 3, 10000 Zagreb, CroatiaDepartment of Diagnostic and Interventional Radiology, University Hospital Dubrava, Avenija Gojka Šuška 6, 10000 Zagreb, CroatiaShear wave elastography (SWE) is a type of ultrasound elastography with which the elastic properties of breast tissues can be quantitatively assessed. The purpose of this study was to determine the impact of different regions of interest (ROI) and lesion size on the performance of SWE in differentiating malignant breast lesions. The study included 150 female patients with histopathologically confirmed malignant breast lesions. Minimal (E<sub>min</sub>), mean (E<sub>mean</sub>), maximal (E<sub>max</sub>) elastic modulus and elasticity ratio (e-ratio) values were measured using a circular ROI size of 2, 4 and 6 mm diameters and the lesions were divided into large (diameter ≥ 15 mm) and small (diameter < 15 mm). Highest E<sub>min</sub>, E<sub>mean</sub> and e-ratio values and lowest variability were observed when using the 2 mm ROI. E<sub>max</sub> values did not differ between different ROI sizes. Larger lesions had significantly higher E<sub>mean</sub> and E<sub>max</sub> values, but there was no difference in e-ratio values between lesions of different sizes. In conclusion, when measuring the E<sub>min</sub>, E<sub>mean</sub> and e-ratio of malignant breast lesions using SWE the smallest possible ROI size should be used regardless of lesion size. ROI size has no impact on E<sub>max</sub> values while lesion size has no impact on e-ratio values.https://www.mdpi.com/2075-4418/11/6/1015breastultrasoundelastographycancerimaging |
| spellingShingle | Antonio Bulum Gordana Ivanac Eugen Divjak Iva Biondić Špoljar Martina Džoić Dominković Kristina Bojanić Marko Lucijanić Boris Brkljačić Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size Diagnostics breast ultrasound elastography cancer imaging |
| title | Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size |
| title_full | Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size |
| title_fullStr | Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size |
| title_full_unstemmed | Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size |
| title_short | Elastic Modulus and Elasticity Ratio of Malignant Breast Lesions with Shear Wave Ultrasound Elastography: Variations with Different Region of Interest and Lesion Size |
| title_sort | elastic modulus and elasticity ratio of malignant breast lesions with shear wave ultrasound elastography variations with different region of interest and lesion size |
| topic | breast ultrasound elastography cancer imaging |
| url | https://www.mdpi.com/2075-4418/11/6/1015 |
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