Influenza vaccine programs for children in low- and middle-income countries: current status and way forward

Introduction: Influenza vaccines are safe and effective, yet they are infrequently used in low- and middle-income countries (LMICs). Areas covered: We examine influenza vaccine programs for children from within a framework of new vaccine adoption in LMICs. We review the available evidence on disease...

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Main Authors: Justin R Ortiz, Kathleen M Neuzil
Format: Article
Language:English
Published: Taylor & Francis Group 2019-07-01
Series:Expert Review of Vaccines
Subjects:
Online Access:http://dx.doi.org/10.1080/14760584.2019.1635462
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author Justin R Ortiz
Kathleen M Neuzil
author_facet Justin R Ortiz
Kathleen M Neuzil
author_sort Justin R Ortiz
collection DOAJ
description Introduction: Influenza vaccines are safe and effective, yet they are infrequently used in low- and middle-income countries (LMICs). Areas covered: We examine influenza vaccine programs for children from within a framework of new vaccine adoption in LMICs. We review the available evidence on disease burden and vaccine introduction, the current global and financing policies, and the current status of vaccine availability, and country readiness for implementation. Expert commentary: Access to appropriate formulations of influenza vaccines and existing immunization infrastructures must be strengthened if influenza vaccine programs are to be expanded in LMICs. While WHO recommends that implementation of influenza vaccine programs should be a country decision based on national goals, capacities, and data review, vaccine decision makers from many LMICs will likely need more evidence to inform the value proposition of program investment for pediatric vaccination, particularly related to alternative immunization strategies that align with current vaccine delivery platforms, anticipated program impact on severe illness endpoints, and program costs and economic benefits. Targeted research and development to address the specific needs of LMICs may be needed to demonstrate the value proposition of influenza vaccines and to expand influenza vaccine programs in these settings.
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spelling doaj.art-1210012da2c343ff9e31bdd5604cd3c32023-09-20T10:18:04ZengTaylor & Francis GroupExpert Review of Vaccines1476-05841744-83952019-07-0118771172410.1080/14760584.2019.16354621635462Influenza vaccine programs for children in low- and middle-income countries: current status and way forwardJustin R Ortiz0Kathleen M Neuzil1University of Maryland School of MedicineUniversity of Maryland School of MedicineIntroduction: Influenza vaccines are safe and effective, yet they are infrequently used in low- and middle-income countries (LMICs). Areas covered: We examine influenza vaccine programs for children from within a framework of new vaccine adoption in LMICs. We review the available evidence on disease burden and vaccine introduction, the current global and financing policies, and the current status of vaccine availability, and country readiness for implementation. Expert commentary: Access to appropriate formulations of influenza vaccines and existing immunization infrastructures must be strengthened if influenza vaccine programs are to be expanded in LMICs. While WHO recommends that implementation of influenza vaccine programs should be a country decision based on national goals, capacities, and data review, vaccine decision makers from many LMICs will likely need more evidence to inform the value proposition of program investment for pediatric vaccination, particularly related to alternative immunization strategies that align with current vaccine delivery platforms, anticipated program impact on severe illness endpoints, and program costs and economic benefits. Targeted research and development to address the specific needs of LMICs may be needed to demonstrate the value proposition of influenza vaccines and to expand influenza vaccine programs in these settings.http://dx.doi.org/10.1080/14760584.2019.1635462influenzainfluenza vaccinelow-resource countryimmunizationpediatrics
spellingShingle Justin R Ortiz
Kathleen M Neuzil
Influenza vaccine programs for children in low- and middle-income countries: current status and way forward
Expert Review of Vaccines
influenza
influenza vaccine
low-resource country
immunization
pediatrics
title Influenza vaccine programs for children in low- and middle-income countries: current status and way forward
title_full Influenza vaccine programs for children in low- and middle-income countries: current status and way forward
title_fullStr Influenza vaccine programs for children in low- and middle-income countries: current status and way forward
title_full_unstemmed Influenza vaccine programs for children in low- and middle-income countries: current status and way forward
title_short Influenza vaccine programs for children in low- and middle-income countries: current status and way forward
title_sort influenza vaccine programs for children in low and middle income countries current status and way forward
topic influenza
influenza vaccine
low-resource country
immunization
pediatrics
url http://dx.doi.org/10.1080/14760584.2019.1635462
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