Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes.

Stroma cell-derived factor-1α signaling enhances calcium transients and beating frequency in rat neonatal cardiomyocytes.

Stroma cell-derived factor-1α (SDF-1α) is a cardioprotective chemokine, acting through its G-protein coupled receptor CXCR4. In experimental acute myocardial infarction, administration of SDF-1α induces an early improvement of systolic function which is difficult to explain solely by an anti-apoptot...

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Bibliographic Details
Main Authors: Ielham Hadad, Alex Veithen, Jean-Yves Springael, Panagiota A Sotiropoulou, Agnès Mendes Da Costa, Françoise Miot, Robert Naeije, Xavier De Deken, Kathleen Mc Entee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3584107?pdf=render

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