Protective Effect of Hexane and Ethanol Extract of L. on Gentamicin-Induced Hair Cell Loss in Neonatal Cultures

Protective Effect of Hexane and Ethanol Extract of L. on Gentamicin-Induced Hair Cell Loss in Neonatal Cultures

ObjectivesGentamicin (GM) is a commonly used aminoglycoside antibiotic that generates free oxygen radicals within the inner ear, which can cause vestibulo-cochlear toxicity and permanent damage to the sensory hair cells and neurons. Piper longum L. (PL) is a well-known spice and traditional medicine...

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Bibliographic Details
Main Authors: Mukesh Kumar Yadav, June Choi, Jae-Jun Song
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2014-03-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Gentamicin
Autotoxicity
Inner hair cell
Outer hair cell
Piper longum
Apoptosis
Antioxidant
Online Access:http://www.e-ceo.org/upload/pdf/ceo-7-13.pdf

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