Stem cell markers in the heart of the human newborn
The identification of cardiac progenitor cells in mammals raises the possibility that the human heart contains a population of stem cells capable of generating cardiomyocytes and coronary vessels. Several recent studies now show that the different cell types that characterize the adult human heart a...
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| Format: | Article |
| Language: | English |
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Hygeia Press di Corridori Marinella
2016-07-01
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| Series: | Journal of Pediatric and Neonatal Individualized Medicine |
| Subjects: | |
| Online Access: | https://www.jpnim.com/index.php/jpnim/article/view/378 |
| _version_ | 1819016824980766720 |
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| author | Armando Faa Elvira Podda Vassilios Fanos |
| author_facet | Armando Faa Elvira Podda Vassilios Fanos |
| author_sort | Armando Faa |
| collection | DOAJ |
| description | The identification of cardiac progenitor cells in mammals raises the possibility that the human heart contains a population of stem cells capable of generating cardiomyocytes and coronary vessels. Several recent studies now show that the different cell types that characterize the adult human heart arise from a common ancestor. Human cardiac stem cells differentiate into cardiomyocytes, and, in lesser extent, into smooth muscle and endothelial cells. The characterization of human cardiac stem cells (CSCs) has important clinical implications. In recent years, CD117 (c-kit) has been reported to mark a subtype of stem/progenitor cells in the human heart, with stem cell-like properties, including the ability to self-renewal and clonogenicity multipotentiality.
Proceedings of the 2nd International Course on Perinatal Pathology (part of the 11th International Workshop on Neonatology · October 26th-31st, 2015) · Cagliari (Italy) · October 31st, 2015 · Stem cells: present and future
Guest Editors: Gavino Faa, Vassilios Fanos, Antonio Giordano |
| first_indexed | 2024-12-21T02:53:47Z |
| format | Article |
| id | doaj.art-1213eef094ba49c59facaa88cb2d8005 |
| institution | Directory Open Access Journal |
| issn | 2281-0692 |
| language | English |
| last_indexed | 2024-12-21T02:53:47Z |
| publishDate | 2016-07-01 |
| publisher | Hygeia Press di Corridori Marinella |
| record_format | Article |
| series | Journal of Pediatric and Neonatal Individualized Medicine |
| spelling | doaj.art-1213eef094ba49c59facaa88cb2d80052022-12-21T19:18:23ZengHygeia Press di Corridori MarinellaJournal of Pediatric and Neonatal Individualized Medicine2281-06922016-07-0152e050204e05020410.7363/050204318Stem cell markers in the heart of the human newbornArmando Faa0Elvira Podda1Vassilios Fanos2Department of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyDepartment of Surgical Sciences, Division of Pathology, University of Cagliari, Cagliari, ItalyNeonatal Intensive Care Unit, Neonatal Pathology, Puericulture Institute and Neonatal Section, AOU and University of Cagliari, Cagliari, ItalyThe identification of cardiac progenitor cells in mammals raises the possibility that the human heart contains a population of stem cells capable of generating cardiomyocytes and coronary vessels. Several recent studies now show that the different cell types that characterize the adult human heart arise from a common ancestor. Human cardiac stem cells differentiate into cardiomyocytes, and, in lesser extent, into smooth muscle and endothelial cells. The characterization of human cardiac stem cells (CSCs) has important clinical implications. In recent years, CD117 (c-kit) has been reported to mark a subtype of stem/progenitor cells in the human heart, with stem cell-like properties, including the ability to self-renewal and clonogenicity multipotentiality. Proceedings of the 2nd International Course on Perinatal Pathology (part of the 11th International Workshop on Neonatology · October 26th-31st, 2015) · Cagliari (Italy) · October 31st, 2015 · Stem cells: present and future Guest Editors: Gavino Faa, Vassilios Fanos, Antonio Giordanohttps://www.jpnim.com/index.php/jpnim/article/view/378stem cellmarkersheartnewborn |
| spellingShingle | Armando Faa Elvira Podda Vassilios Fanos Stem cell markers in the heart of the human newborn Journal of Pediatric and Neonatal Individualized Medicine stem cell markers heart newborn |
| title | Stem cell markers in the heart of the human newborn |
| title_full | Stem cell markers in the heart of the human newborn |
| title_fullStr | Stem cell markers in the heart of the human newborn |
| title_full_unstemmed | Stem cell markers in the heart of the human newborn |
| title_short | Stem cell markers in the heart of the human newborn |
| title_sort | stem cell markers in the heart of the human newborn |
| topic | stem cell markers heart newborn |
| url | https://www.jpnim.com/index.php/jpnim/article/view/378 |
| work_keys_str_mv | AT armandofaa stemcellmarkersintheheartofthehumannewborn AT elvirapodda stemcellmarkersintheheartofthehumannewborn AT vassiliosfanos stemcellmarkersintheheartofthehumannewborn |