Infection of Human Macrophages by Leishmania infantum Is Influenced by Ecto-Nucleotidases

Infection of Human Macrophages by Leishmania infantum Is Influenced by Ecto-Nucleotidases

Ecto-nucleotidase activity is involved in the infection process of Leishmania and various other parasites that enables modulation of host immune responses to promote disease progression. One of the enzymes responsible for this activity is the ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDas...

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Main Authors: Nalu Teixeira de Aguiar Peres, Luana Celina Seraphim Cunha, Meirielly Lima Almeida Barbosa, Márcio Bezerra Santos, Fabrícia Alvise de Oliveira, Amélia Maria Ribeiro de Jesus, Roque Pacheco de Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
Leishmania infantum
macrophage
infection
ecto-nucleotidase
extracellular nucleotides
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01954/full

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