Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study.
<h4>Background</h4>Rate of cesarean section (CS), including elective CS has globally increased. Studies have found that term elective CS before 39 weeks of gestation is associated with increased risk of adverse respiratory outcomes.<h4>Objective</h4>To determine the rate of e...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0249557 |
| _version_ | 1819003592139341824 |
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| author | Ayah Al Bizri Nansi S Boghossian Anwar Nassar Pascale Nakad Dina Jaber Rabih Chahine Gaby Fallakha Ghaith Makhoul Khalid Yunis |
| author_facet | Ayah Al Bizri Nansi S Boghossian Anwar Nassar Pascale Nakad Dina Jaber Rabih Chahine Gaby Fallakha Ghaith Makhoul Khalid Yunis |
| author_sort | Ayah Al Bizri |
| collection | DOAJ |
| description | <h4>Background</h4>Rate of cesarean section (CS), including elective CS has globally increased. Studies have found that term elective CS before 39 weeks of gestation is associated with increased risk of adverse respiratory outcomes.<h4>Objective</h4>To determine the rate of elective CS and examine the association between timing of elective term CS and adverse neonatal outcomes in a large population of Lebanese women.<h4>Methods</h4>A Multi-Center Study was conducted using data from the National Collaborative Perinatal Neonatal Network database. Simple and multivariable logistic regression models were used to examine the association between timing of term elective CS and adverse neonatal outcomes. Some of the neonatal adverse outcomes we examined included respiratory distress syndrome, admission to the NICU, and a composite of respiratory outcomes.<h4>Results</h4>A total of 28,997 low risk mothers who delivered through primary and repeat elective CS were included in the study. Uncomplicated elective planned term CS constituted 25% of all CS deliveries in Lebanon. Primary and repeat CS at 37 weeks of gestation increased the odds of most of the studied adverse neonatal outcomes. There were few associations between CS and adverse neonatal outcomes at 38 weeks of gestation.<h4>Conclusions</h4>Term primary and repeat cesarean delivery prior to 39 weeks of gestation is associated with respiratory and other adverse neonatal outcomes. Delaying birth 1-2 weeks till 39 weeks of gestation can prevent 64-77% of adverse respiratory outcomes. |
| first_indexed | 2024-12-20T23:23:27Z |
| format | Article |
| id | doaj.art-1215680523174ff18f8e39d47bac55d8 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-20T23:23:27Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-1215680523174ff18f8e39d47bac55d82022-12-21T19:23:27ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-01164e024955710.1371/journal.pone.0249557Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study.Ayah Al BizriNansi S BoghossianAnwar NassarPascale NakadDina JaberRabih ChahineGaby FallakhaGhaith MakhoulKhalid Yunis<h4>Background</h4>Rate of cesarean section (CS), including elective CS has globally increased. Studies have found that term elective CS before 39 weeks of gestation is associated with increased risk of adverse respiratory outcomes.<h4>Objective</h4>To determine the rate of elective CS and examine the association between timing of elective term CS and adverse neonatal outcomes in a large population of Lebanese women.<h4>Methods</h4>A Multi-Center Study was conducted using data from the National Collaborative Perinatal Neonatal Network database. Simple and multivariable logistic regression models were used to examine the association between timing of term elective CS and adverse neonatal outcomes. Some of the neonatal adverse outcomes we examined included respiratory distress syndrome, admission to the NICU, and a composite of respiratory outcomes.<h4>Results</h4>A total of 28,997 low risk mothers who delivered through primary and repeat elective CS were included in the study. Uncomplicated elective planned term CS constituted 25% of all CS deliveries in Lebanon. Primary and repeat CS at 37 weeks of gestation increased the odds of most of the studied adverse neonatal outcomes. There were few associations between CS and adverse neonatal outcomes at 38 weeks of gestation.<h4>Conclusions</h4>Term primary and repeat cesarean delivery prior to 39 weeks of gestation is associated with respiratory and other adverse neonatal outcomes. Delaying birth 1-2 weeks till 39 weeks of gestation can prevent 64-77% of adverse respiratory outcomes.https://doi.org/10.1371/journal.pone.0249557 |
| spellingShingle | Ayah Al Bizri Nansi S Boghossian Anwar Nassar Pascale Nakad Dina Jaber Rabih Chahine Gaby Fallakha Ghaith Makhoul Khalid Yunis Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study. PLoS ONE |
| title | Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study. |
| title_full | Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study. |
| title_fullStr | Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study. |
| title_full_unstemmed | Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study. |
| title_short | Timing of term elective cesarean section and adverse neonatal outcomes: A multi-center retrospective cohort study. |
| title_sort | timing of term elective cesarean section and adverse neonatal outcomes a multi center retrospective cohort study |
| url | https://doi.org/10.1371/journal.pone.0249557 |
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