Boundary Associated Long Noncoding RNA Mediates Long-Range Chromosomal Interactions.

CCCTC binding factor (CTCF) is involved in organizing chromosomes into mega base-sized, topologically associated domains (TADs) along with other factors that define sub-TAD organization. CTCF-Cohesin interactions have been shown to be critical for transcription insulation activity as it stabilizes l...

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Bibliographic Details
Main Authors: Ifeoma Jane Nwigwe, Yoon Jung Kim, David A Wacker, Tae Hoon Kim
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4547746?pdf=render