Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey
Introduction: Vitamin D Deficiency (VDD) and several other metabolic factors are known to be involved in the aggravation of Osteoarthritis (OA). A better understanding of the role of these metabolic factors and diseases is required to alleviate the OA progression. Aim: To analyse the prevalence...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2021-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/15279/48364_CE[Ra1]_F[IK]_PF1(AB_SHU_KM)_PN(KM).pdf |
| Summary: | Introduction: Vitamin D Deficiency (VDD) and several other
metabolic factors are known to be involved in the aggravation of
Osteoarthritis (OA). A better understanding of the role of these
metabolic factors and diseases is required to alleviate the OA
progression.
Aim: To analyse the prevalence of VDD in OA patients and its
correlation with co-morbidities such as diabetes, hypertension
(HT), Cardiovascular Disease (CVD) and acidity and also to
assess the effect of Body Mass Index (BMI) and increasing age
on the developmental process of OA.
Materials and Methods: A cross-sectional survey was
undertaken during September 2018 to March 2019 in King
Khaled, King Salman and Hail General Hospitals located in
Ha’il province of Kingdom of Saudi Arabia (KSA). The study
included 501 participants of OA patients that visited these
hospitals. Data pertaining to the variables in this study such as
diabetes, HT, cardiovascular problems, vitamin D and calcium
deficiency, acidity and anthropometric details was obtained
using a structured questionnaire. Data analysis was done
using descriptive statistics and Pearson’s correlation with the
statistical program SPSS version 21.
Results: VDD, calcium deficiency and acidity were the most
prevalent factors observed in the patients. Vitamin D and
calcium deficiency was observed to be higher in females than
males. VDD significantly correlated to diabetes, HT, acidity
and age, both in females and males. Cardiovascular disease
and BMI correlated with VDD only in males but not in females.
BMI showed positive correlation with HT in males (p<0.01) but
not females, and also correlated with age (p<0.01) irrespective
of gender.
Conclusion: The study concluded that VDD is more prevalent
in females than males in Ha’il region. It is correlated to
variables such as diabetes, HT, acidity, BMI and increasing
age, which are identified as risk factors contributing to the
progression of OA. |
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| ISSN: | 2249-782X 0973-709X |