Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey
Introduction: Vitamin D Deficiency (VDD) and several other metabolic factors are known to be involved in the aggravation of Osteoarthritis (OA). A better understanding of the role of these metabolic factors and diseases is required to alleviate the OA progression. Aim: To analyse the prevalence...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2021-08-01
|
| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/15279/48364_CE[Ra1]_F[IK]_PF1(AB_SHU_KM)_PN(KM).pdf |
| _version_ | 1819117462867673088 |
|---|---|
| author | Ramadevi Kundur Ramaiah Itumalla Eitimad Hashim Abdel-Rahman Malak Saad Althawainy |
| author_facet | Ramadevi Kundur Ramaiah Itumalla Eitimad Hashim Abdel-Rahman Malak Saad Althawainy |
| author_sort | Ramadevi Kundur |
| collection | DOAJ |
| description | Introduction: Vitamin D Deficiency (VDD) and several other
metabolic factors are known to be involved in the aggravation of
Osteoarthritis (OA). A better understanding of the role of these
metabolic factors and diseases is required to alleviate the OA
progression.
Aim: To analyse the prevalence of VDD in OA patients and its
correlation with co-morbidities such as diabetes, hypertension
(HT), Cardiovascular Disease (CVD) and acidity and also to
assess the effect of Body Mass Index (BMI) and increasing age
on the developmental process of OA.
Materials and Methods: A cross-sectional survey was
undertaken during September 2018 to March 2019 in King
Khaled, King Salman and Hail General Hospitals located in
Ha’il province of Kingdom of Saudi Arabia (KSA). The study
included 501 participants of OA patients that visited these
hospitals. Data pertaining to the variables in this study such as
diabetes, HT, cardiovascular problems, vitamin D and calcium
deficiency, acidity and anthropometric details was obtained
using a structured questionnaire. Data analysis was done
using descriptive statistics and Pearson’s correlation with the
statistical program SPSS version 21.
Results: VDD, calcium deficiency and acidity were the most
prevalent factors observed in the patients. Vitamin D and
calcium deficiency was observed to be higher in females than
males. VDD significantly correlated to diabetes, HT, acidity
and age, both in females and males. Cardiovascular disease
and BMI correlated with VDD only in males but not in females.
BMI showed positive correlation with HT in males (p<0.01) but
not females, and also correlated with age (p<0.01) irrespective
of gender.
Conclusion: The study concluded that VDD is more prevalent
in females than males in Ha’il region. It is correlated to
variables such as diabetes, HT, acidity, BMI and increasing
age, which are identified as risk factors contributing to the
progression of OA. |
| first_indexed | 2024-12-22T05:33:22Z |
| format | Article |
| id | doaj.art-121e770b269b48f39f6859d3db70322c |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-22T05:33:22Z |
| publishDate | 2021-08-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-121e770b269b48f39f6859d3db70322c2022-12-21T18:37:23ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-08-01158LC17LC2010.7860/JCDR/2021/48364.15279Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional SurveyRamadevi Kundur0Ramaiah Itumalla1Eitimad Hashim Abdel-Rahman2Malak Saad Althawainy3Assistant Professor, Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Ha’il, Saudi Arabia.Assistant Professor, Department of Health Management, College of Public Health and Health Informatics, University of Ha’il, Ha’il, Saudi Arabia.Assistant Professor, Open Arab University, Sudan Branch Khartoum st. 21 Amarrat Khartoum, Sudan.Student, Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Ha’il, Saudi Arabia.Introduction: Vitamin D Deficiency (VDD) and several other metabolic factors are known to be involved in the aggravation of Osteoarthritis (OA). A better understanding of the role of these metabolic factors and diseases is required to alleviate the OA progression. Aim: To analyse the prevalence of VDD in OA patients and its correlation with co-morbidities such as diabetes, hypertension (HT), Cardiovascular Disease (CVD) and acidity and also to assess the effect of Body Mass Index (BMI) and increasing age on the developmental process of OA. Materials and Methods: A cross-sectional survey was undertaken during September 2018 to March 2019 in King Khaled, King Salman and Hail General Hospitals located in Ha’il province of Kingdom of Saudi Arabia (KSA). The study included 501 participants of OA patients that visited these hospitals. Data pertaining to the variables in this study such as diabetes, HT, cardiovascular problems, vitamin D and calcium deficiency, acidity and anthropometric details was obtained using a structured questionnaire. Data analysis was done using descriptive statistics and Pearson’s correlation with the statistical program SPSS version 21. Results: VDD, calcium deficiency and acidity were the most prevalent factors observed in the patients. Vitamin D and calcium deficiency was observed to be higher in females than males. VDD significantly correlated to diabetes, HT, acidity and age, both in females and males. Cardiovascular disease and BMI correlated with VDD only in males but not in females. BMI showed positive correlation with HT in males (p<0.01) but not females, and also correlated with age (p<0.01) irrespective of gender. Conclusion: The study concluded that VDD is more prevalent in females than males in Ha’il region. It is correlated to variables such as diabetes, HT, acidity, BMI and increasing age, which are identified as risk factors contributing to the progression of OA.https://jcdr.net/articles/PDF/15279/48364_CE[Ra1]_F[IK]_PF1(AB_SHU_KM)_PN(KM).pdfbody mass indexcardiovascular diseasediabeteshypertension |
| spellingShingle | Ramadevi Kundur Ramaiah Itumalla Eitimad Hashim Abdel-Rahman Malak Saad Althawainy Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey Journal of Clinical and Diagnostic Research body mass index cardiovascular disease diabetes hypertension |
| title | Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey |
| title_full | Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey |
| title_fullStr | Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey |
| title_full_unstemmed | Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey |
| title_short | Prevalence of Vitamin D Deficiency and Its Associated Risk Factors on Osteoarthritis: A Cross-sectional Survey |
| title_sort | prevalence of vitamin d deficiency and its associated risk factors on osteoarthritis a cross sectional survey |
| topic | body mass index cardiovascular disease diabetes hypertension |
| url | https://jcdr.net/articles/PDF/15279/48364_CE[Ra1]_F[IK]_PF1(AB_SHU_KM)_PN(KM).pdf |
| work_keys_str_mv | AT ramadevikundur prevalenceofvitaminddeficiencyanditsassociatedriskfactorsonosteoarthritisacrosssectionalsurvey AT ramaiahitumalla prevalenceofvitaminddeficiencyanditsassociatedriskfactorsonosteoarthritisacrosssectionalsurvey AT eitimadhashimabdelrahman prevalenceofvitaminddeficiencyanditsassociatedriskfactorsonosteoarthritisacrosssectionalsurvey AT malaksaadalthawainy prevalenceofvitaminddeficiencyanditsassociatedriskfactorsonosteoarthritisacrosssectionalsurvey |