Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis
BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has posed increasing challenges to global health systems. Vaccination against COVID-19 can effectively prevent the public, particularly healthcare workers (HCWs), from being infected by this disease.ObjectivesWe aim to understand the factors...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2022.881903/full |
| _version_ | 1828230918047793152 |
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| author | Linlin Wang Ye Wang Xianbin Cheng Xingzhao Li Yanyan Yang Jun Li |
| author_facet | Linlin Wang Ye Wang Xianbin Cheng Xingzhao Li Yanyan Yang Jun Li |
| author_sort | Linlin Wang |
| collection | DOAJ |
| description | BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has posed increasing challenges to global health systems. Vaccination against COVID-19 can effectively prevent the public, particularly healthcare workers (HCWs), from being infected by this disease.ObjectivesWe aim to understand the factors influencing HCWs' acceptance of COVID-19 vaccines.MethodsWe searched PubMed, Embase and Web of Science to collect literature published before May 15, 2022, about HCWs' acceptance of COVID-19 vaccines. The Newcastle–Ottawa quality assessment scale was used to assess the risk of bias and the quality of the included studies. We utilized Stata 14.0 software for this meta-analysis with a random-effects model, and odds ratios (ORs) with 95% confidence intervals (CIs) were reported. This meta-analysis was conducted in alignment with the preferred reporting items for systematic review and meta-analysis (PRISMA) guideline.ResultsOur meta-analysis included 71 articles with 93,508 HCWs involved. The research showed that the acceptance of vaccines had significantly increased among HCWs compared to non-HCWs (OR = 1.91, 95% CI: 1.16–3.12). A willingness to undergo COVID-19 vaccination was observed in 66% (95% CI: 0.61–0.67) of HCWs. Among the HCWs involved, doctors showed a generally increased intention to be vaccinated compared with nurses (OR = 2.22, 95% CI: 1.71–2.89). Additionally, males were found to hold more positive attitudes toward vaccination than females (OR = 1.81, 95% CI: 1.55–2.12). When the effectiveness of COVID-19 vaccines was improved, the vaccination acceptance of HCWs was greatly increased accordingly (OR = 5.03, 95% CI: 2.77–9.11). The HCWs who were willing to vaccinate against seasonal influenza showed an increased acceptance of COVID-19 vaccines (OR = 3.52, 95% CI: 2.34–5.28). Our study also showed that HCWs who were willing to be vaccinated against COVID-19 experienced a reduced rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (OR = 0.78, 95% CI: 0.66–0.92).ConclusionsOur analysis revealed that the five factors of occupation, gender, vaccine effectiveness, seasonal influenza vaccines, and SARS-CoV-2 infection presumably affected the acceptance of COVID-19 vaccines among HCWs. It is essential to boost the confidence of HCWs in COVID-19 vaccines for the containment of the epidemic. |
| first_indexed | 2024-04-12T18:55:26Z |
| format | Article |
| id | doaj.art-1220bb0bfe95408a898c82caa22a2b53 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-04-12T18:55:26Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-1220bb0bfe95408a898c82caa22a2b532022-12-22T03:20:20ZengFrontiers Media S.A.Frontiers in Public Health2296-25652022-09-011010.3389/fpubh.2022.881903881903Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysisLinlin Wang0Ye Wang1Xianbin Cheng2Xingzhao Li3Yanyan Yang4Jun Li5Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Pediatrics, China-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, ChinaDepartment of Hematology and Oncology, China-Japan Union Hospital of Jilin University, Changchun, ChinaBackgroundThe coronavirus disease 2019 (COVID-19) pandemic has posed increasing challenges to global health systems. Vaccination against COVID-19 can effectively prevent the public, particularly healthcare workers (HCWs), from being infected by this disease.ObjectivesWe aim to understand the factors influencing HCWs' acceptance of COVID-19 vaccines.MethodsWe searched PubMed, Embase and Web of Science to collect literature published before May 15, 2022, about HCWs' acceptance of COVID-19 vaccines. The Newcastle–Ottawa quality assessment scale was used to assess the risk of bias and the quality of the included studies. We utilized Stata 14.0 software for this meta-analysis with a random-effects model, and odds ratios (ORs) with 95% confidence intervals (CIs) were reported. This meta-analysis was conducted in alignment with the preferred reporting items for systematic review and meta-analysis (PRISMA) guideline.ResultsOur meta-analysis included 71 articles with 93,508 HCWs involved. The research showed that the acceptance of vaccines had significantly increased among HCWs compared to non-HCWs (OR = 1.91, 95% CI: 1.16–3.12). A willingness to undergo COVID-19 vaccination was observed in 66% (95% CI: 0.61–0.67) of HCWs. Among the HCWs involved, doctors showed a generally increased intention to be vaccinated compared with nurses (OR = 2.22, 95% CI: 1.71–2.89). Additionally, males were found to hold more positive attitudes toward vaccination than females (OR = 1.81, 95% CI: 1.55–2.12). When the effectiveness of COVID-19 vaccines was improved, the vaccination acceptance of HCWs was greatly increased accordingly (OR = 5.03, 95% CI: 2.77–9.11). The HCWs who were willing to vaccinate against seasonal influenza showed an increased acceptance of COVID-19 vaccines (OR = 3.52, 95% CI: 2.34–5.28). Our study also showed that HCWs who were willing to be vaccinated against COVID-19 experienced a reduced rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (OR = 0.78, 95% CI: 0.66–0.92).ConclusionsOur analysis revealed that the five factors of occupation, gender, vaccine effectiveness, seasonal influenza vaccines, and SARS-CoV-2 infection presumably affected the acceptance of COVID-19 vaccines among HCWs. It is essential to boost the confidence of HCWs in COVID-19 vaccines for the containment of the epidemic.https://www.frontiersin.org/articles/10.3389/fpubh.2022.881903/fullCOVID-19vaccinesmeta-analysisseasonal influenzahealthcare workers |
| spellingShingle | Linlin Wang Ye Wang Xianbin Cheng Xingzhao Li Yanyan Yang Jun Li Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis Frontiers in Public Health COVID-19 vaccines meta-analysis seasonal influenza healthcare workers |
| title | Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis |
| title_full | Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis |
| title_fullStr | Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis |
| title_full_unstemmed | Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis |
| title_short | Acceptance of coronavirus disease 2019 (COVID-19) vaccines among healthcare workers: A meta-analysis |
| title_sort | acceptance of coronavirus disease 2019 covid 19 vaccines among healthcare workers a meta analysis |
| topic | COVID-19 vaccines meta-analysis seasonal influenza healthcare workers |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2022.881903/full |
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