Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020
Alzheimer's disease (AD) is currently one of the main diseases afflicting the elderly in the world. In recent years, more and more studies have shown that brain energy metabolism disorders are the key pathogenic factors and main early pathological features of AD. Many risk factors such as insul...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2021-07-01
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Series: | Frontiers in Neurology |
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Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2021.670220/full |
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author | Yi-Hong Du Yi-Hong Du Ruo-Yu Yang Qi Wang Li-Yan Wang Lei-Chao Liang Lei Zhu Yan Sun Ming Cai |
author_facet | Yi-Hong Du Yi-Hong Du Ruo-Yu Yang Qi Wang Li-Yan Wang Lei-Chao Liang Lei Zhu Yan Sun Ming Cai |
author_sort | Yi-Hong Du |
collection | DOAJ |
description | Alzheimer's disease (AD) is currently one of the main diseases afflicting the elderly in the world. In recent years, more and more studies have shown that brain energy metabolism disorders are the key pathogenic factors and main early pathological features of AD. Many risk factors such as insulin resistance, mitochondrial dysfunction, oxidative stress, Aβ-amyloid plaques, neurofibrillary tangles of hyperphosphorylated tau, aging, and neuroinflammation are involved in brain energy metabolism disorders. In this study, 1,379 Web of Science publications on the mechanisms of brain energy metabolism disorders in AD, all published from 2000 to 2020, were analyzed. Some network maps were drawn using CiteSpace and VOSviewer software which can be used to clarify research focus, forecast research frontiers and development trends, and provide different perspectives and characteristics in AD brain energy metabolism disorder mechanisms. |
first_indexed | 2024-12-22T14:35:55Z |
format | Article |
id | doaj.art-12245c7fa4ff476189c50238bf81753c |
institution | Directory Open Access Journal |
issn | 1664-2295 |
language | English |
last_indexed | 2024-12-22T14:35:55Z |
publishDate | 2021-07-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Neurology |
spelling | doaj.art-12245c7fa4ff476189c50238bf81753c2022-12-21T18:22:38ZengFrontiers Media S.A.Frontiers in Neurology1664-22952021-07-011210.3389/fneur.2021.670220670220Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020Yi-Hong Du0Yi-Hong Du1Ruo-Yu Yang2Qi Wang3Li-Yan Wang4Lei-Chao Liang5Lei Zhu6Yan Sun7Ming Cai8Shanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, ChinaCollege of Physical and Health, East China Jiaotong University, Nanchang, ChinaCollege of Rehabilitation Science, Shanghai University of Medicine and Health Sciences, Shanghai, ChinaCollege of Sport Sciences, Qufu Normal University, Qufu, ChinaCollege of Rehabilitation Science, Shanghai University of Medicine and Health Sciences, Shanghai, ChinaCollege of Rehabilitation Science, Shanghai University of Medicine and Health Sciences, Shanghai, ChinaCollege of Sport Sciences, Qufu Normal University, Qufu, ChinaCollege of Physical and Health, East China Jiaotong University, Nanchang, ChinaShanghai University of Medicine and Health Sciences Affiliated Zhoupu Hospital, Shanghai, ChinaAlzheimer's disease (AD) is currently one of the main diseases afflicting the elderly in the world. In recent years, more and more studies have shown that brain energy metabolism disorders are the key pathogenic factors and main early pathological features of AD. Many risk factors such as insulin resistance, mitochondrial dysfunction, oxidative stress, Aβ-amyloid plaques, neurofibrillary tangles of hyperphosphorylated tau, aging, and neuroinflammation are involved in brain energy metabolism disorders. In this study, 1,379 Web of Science publications on the mechanisms of brain energy metabolism disorders in AD, all published from 2000 to 2020, were analyzed. Some network maps were drawn using CiteSpace and VOSviewer software which can be used to clarify research focus, forecast research frontiers and development trends, and provide different perspectives and characteristics in AD brain energy metabolism disorder mechanisms.https://www.frontiersin.org/articles/10.3389/fneur.2021.670220/fullAlzheimer's diseasebrain energy metabolismbibliometric analysisWeb of ScienceCiteSpaceVOSviewer |
spellingShingle | Yi-Hong Du Yi-Hong Du Ruo-Yu Yang Qi Wang Li-Yan Wang Lei-Chao Liang Lei Zhu Yan Sun Ming Cai Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 Frontiers in Neurology Alzheimer's disease brain energy metabolism bibliometric analysis Web of Science CiteSpace VOSviewer |
title | Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 |
title_full | Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 |
title_fullStr | Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 |
title_full_unstemmed | Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 |
title_short | Bibliometric Analysis Study on the Mechanisms of Brain Energy Metabolism Disorders in Alzheimer's Disease From 2000 to 2020 |
title_sort | bibliometric analysis study on the mechanisms of brain energy metabolism disorders in alzheimer s disease from 2000 to 2020 |
topic | Alzheimer's disease brain energy metabolism bibliometric analysis Web of Science CiteSpace VOSviewer |
url | https://www.frontiersin.org/articles/10.3389/fneur.2021.670220/full |
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