A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, sin...
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MDPI AG
2022-01-01
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Series: | Micromachines |
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Online Access: | https://www.mdpi.com/2072-666X/13/2/188 |
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author | Amirreza Ghaznavi Yang Lin Mark Douvidzon Adam Szmelter Alannah Rodrigues Malik Blackman David Eddington Tal Carmon Lev Deych Lan Yang Jie Xu |
author_facet | Amirreza Ghaznavi Yang Lin Mark Douvidzon Adam Szmelter Alannah Rodrigues Malik Blackman David Eddington Tal Carmon Lev Deych Lan Yang Jie Xu |
author_sort | Amirreza Ghaznavi |
collection | DOAJ |
description | We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, single and compound emulsions of deionized water and mineral oil were generated and their features such as size, generation frequency, and emulsion structures were successfully characterized. In addition, the generation of bio emulsions such as alginate and collagen aqueous droplets in mineral oil was demonstrated in this study. Overall, the monolithic 3D printed axisymmetric droplet generator could offer any user an accessible and easy-to-utilize device for the generation of single and compound emulsions. |
first_indexed | 2024-03-09T21:25:18Z |
format | Article |
id | doaj.art-1225b57c0dc54c2394a533cc37a43fa3 |
institution | Directory Open Access Journal |
issn | 2072-666X |
language | English |
last_indexed | 2024-03-09T21:25:18Z |
publishDate | 2022-01-01 |
publisher | MDPI AG |
record_format | Article |
series | Micromachines |
spelling | doaj.art-1225b57c0dc54c2394a533cc37a43fa32023-11-23T21:10:00ZengMDPI AGMicromachines2072-666X2022-01-0113218810.3390/mi13020188A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion GeneratorAmirreza Ghaznavi0Yang Lin1Mark Douvidzon2Adam Szmelter3Alannah Rodrigues4Malik Blackman5David Eddington6Tal Carmon7Lev Deych8Lan Yang9Jie Xu10Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL 60607, USADepartment of Mechanical, Industrial and Systems Engineering, University of Rhode Island, Kingston, RI 02881, USAPhysics Department and Solid-State Institute, Technion, Haifa 3200000, IsraelDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USADepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USADepartment of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USADepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USASchool of Electrical Engineering, Tel Aviv University, Tel Aviv-Yafo 6997801, IsraelPhysics Department, Queens College of CUNY, New York, NY 11367, USADepartment of Electrical and Systems Engineering, Washington University, St. Louis, MO 63130, USADepartment of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL 60607, USAWe report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, single and compound emulsions of deionized water and mineral oil were generated and their features such as size, generation frequency, and emulsion structures were successfully characterized. In addition, the generation of bio emulsions such as alginate and collagen aqueous droplets in mineral oil was demonstrated in this study. Overall, the monolithic 3D printed axisymmetric droplet generator could offer any user an accessible and easy-to-utilize device for the generation of single and compound emulsions.https://www.mdpi.com/2072-666X/13/2/188emulsion generatorcompound droplets3D printingmicrofluidic devicemicrofluidics |
spellingShingle | Amirreza Ghaznavi Yang Lin Mark Douvidzon Adam Szmelter Alannah Rodrigues Malik Blackman David Eddington Tal Carmon Lev Deych Lan Yang Jie Xu A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator Micromachines emulsion generator compound droplets 3D printing microfluidic device microfluidics |
title | A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator |
title_full | A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator |
title_fullStr | A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator |
title_full_unstemmed | A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator |
title_short | A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator |
title_sort | monolithic 3d printed axisymmetric co flow single and compound emulsion generator |
topic | emulsion generator compound droplets 3D printing microfluidic device microfluidics |
url | https://www.mdpi.com/2072-666X/13/2/188 |
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