A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator

We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, sin...

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Main Authors: Amirreza Ghaznavi, Yang Lin, Mark Douvidzon, Adam Szmelter, Alannah Rodrigues, Malik Blackman, David Eddington, Tal Carmon, Lev Deych, Lan Yang, Jie Xu
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/13/2/188
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author Amirreza Ghaznavi
Yang Lin
Mark Douvidzon
Adam Szmelter
Alannah Rodrigues
Malik Blackman
David Eddington
Tal Carmon
Lev Deych
Lan Yang
Jie Xu
author_facet Amirreza Ghaznavi
Yang Lin
Mark Douvidzon
Adam Szmelter
Alannah Rodrigues
Malik Blackman
David Eddington
Tal Carmon
Lev Deych
Lan Yang
Jie Xu
author_sort Amirreza Ghaznavi
collection DOAJ
description We report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, single and compound emulsions of deionized water and mineral oil were generated and their features such as size, generation frequency, and emulsion structures were successfully characterized. In addition, the generation of bio emulsions such as alginate and collagen aqueous droplets in mineral oil was demonstrated in this study. Overall, the monolithic 3D printed axisymmetric droplet generator could offer any user an accessible and easy-to-utilize device for the generation of single and compound emulsions.
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spelling doaj.art-1225b57c0dc54c2394a533cc37a43fa32023-11-23T21:10:00ZengMDPI AGMicromachines2072-666X2022-01-0113218810.3390/mi13020188A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion GeneratorAmirreza Ghaznavi0Yang Lin1Mark Douvidzon2Adam Szmelter3Alannah Rodrigues4Malik Blackman5David Eddington6Tal Carmon7Lev Deych8Lan Yang9Jie Xu10Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL 60607, USADepartment of Mechanical, Industrial and Systems Engineering, University of Rhode Island, Kingston, RI 02881, USAPhysics Department and Solid-State Institute, Technion, Haifa 3200000, IsraelDepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USADepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USADepartment of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USADepartment of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USASchool of Electrical Engineering, Tel Aviv University, Tel Aviv-Yafo 6997801, IsraelPhysics Department, Queens College of CUNY, New York, NY 11367, USADepartment of Electrical and Systems Engineering, Washington University, St. Louis, MO 63130, USADepartment of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, IL 60607, USAWe report a microfluidic droplet generator which can produce single and compound droplets using a 3D axisymmetric co-flow structure. The design considered for the fabrication of the device integrated a user-friendly and cost-effective 3D printing process. To verify the performance of the device, single and compound emulsions of deionized water and mineral oil were generated and their features such as size, generation frequency, and emulsion structures were successfully characterized. In addition, the generation of bio emulsions such as alginate and collagen aqueous droplets in mineral oil was demonstrated in this study. Overall, the monolithic 3D printed axisymmetric droplet generator could offer any user an accessible and easy-to-utilize device for the generation of single and compound emulsions.https://www.mdpi.com/2072-666X/13/2/188emulsion generatorcompound droplets3D printingmicrofluidic devicemicrofluidics
spellingShingle Amirreza Ghaznavi
Yang Lin
Mark Douvidzon
Adam Szmelter
Alannah Rodrigues
Malik Blackman
David Eddington
Tal Carmon
Lev Deych
Lan Yang
Jie Xu
A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
Micromachines
emulsion generator
compound droplets
3D printing
microfluidic device
microfluidics
title A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_full A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_fullStr A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_full_unstemmed A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_short A Monolithic 3D Printed Axisymmetric Co-Flow Single and Compound Emulsion Generator
title_sort monolithic 3d printed axisymmetric co flow single and compound emulsion generator
topic emulsion generator
compound droplets
3D printing
microfluidic device
microfluidics
url https://www.mdpi.com/2072-666X/13/2/188
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