Folic acid‐modified nonionic surfactant vesicles for gambogenic acid targeting: Preparation, characterization, and in vitro and in vivo evaluation

Folic acid‐modified nonionic surfactant vesicles for gambogenic acid targeting: Preparation, characterization, and in vitro and in vivo evaluation

Abstract The aim of present study was to develop folic acid (FA)‐modified nonionic surfactant vesicles (NISVs, niosomes) as carrier systems for targeted delivery of gambogenic acid (GNA). The FA‐GNA‐NISVs exhibited a mean particle size of 180.77 ± 2.41 nm with a narrow poly dispersion index of 0.147...

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Bibliographic Details
Main Authors: Tong‐Yuan Lin, Jia‐Li Chang, Yan Xun, Yi Zhao, Wang Peng, Wang Yang, Bai‐Jing Ding, Wei‐Dong Chen
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
folic acid
gambogenic acid
nonionic surfactant vesicles
targeted delivery
Online Access:https://doi.org/10.1002/kjm2.12162

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