Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments
Nontuberculous mycobacterial pulmonary disease (NTM-PD) remains a challenging condition to diagnose and treat effectively. Treatment of NTM-PD is prolonged, frequently associated with adverse effects and has variable success. In this review, we consider the factors influencing clinicians when treati...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2022-02-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/31/163/210212.full |
| _version_ | 1818364608378830848 |
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| author | Kartik Kumar Charles L. Daley David E. Griffith Michael R. Loebinger |
| author_facet | Kartik Kumar Charles L. Daley David E. Griffith Michael R. Loebinger |
| author_sort | Kartik Kumar |
| collection | DOAJ |
| description | Nontuberculous mycobacterial pulmonary disease (NTM-PD) remains a challenging condition to diagnose and treat effectively. Treatment of NTM-PD is prolonged, frequently associated with adverse effects and has variable success. In this review, we consider the factors influencing clinicians when treating NTM-PD and discuss outcomes from key studies on the pharmacological management of Mycobacterium avium complex pulmonary disease and M. abscessus pulmonary disease. We highlight issues relating to treatment-related toxicity and provide an overview of repurposed and emerging therapies for NTM-PD. |
| first_indexed | 2024-12-13T22:07:04Z |
| format | Article |
| id | doaj.art-122af0c2ad194141bd3fe14bc292097a |
| institution | Directory Open Access Journal |
| issn | 0905-9180 1600-0617 |
| language | English |
| last_indexed | 2024-12-13T22:07:04Z |
| publishDate | 2022-02-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | European Respiratory Review |
| spelling | doaj.art-122af0c2ad194141bd3fe14bc292097a2022-12-21T23:29:49ZengEuropean Respiratory SocietyEuropean Respiratory Review0905-91801600-06172022-02-013116310.1183/16000617.0212-20210212-2021Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatmentsKartik Kumar0Charles L. Daley1David E. Griffith2Michael R. Loebinger3 National Heart and Lung Institute, Imperial College London, London, UK Division of Mycobacterial and Respiratory Infections, Dept of Medicine, National Jewish Health, Denver, CO, USA Division of Mycobacterial and Respiratory Infections, Dept of Medicine, National Jewish Health, Denver, CO, USA National Heart and Lung Institute, Imperial College London, London, UK Nontuberculous mycobacterial pulmonary disease (NTM-PD) remains a challenging condition to diagnose and treat effectively. Treatment of NTM-PD is prolonged, frequently associated with adverse effects and has variable success. In this review, we consider the factors influencing clinicians when treating NTM-PD and discuss outcomes from key studies on the pharmacological management of Mycobacterium avium complex pulmonary disease and M. abscessus pulmonary disease. We highlight issues relating to treatment-related toxicity and provide an overview of repurposed and emerging therapies for NTM-PD.http://err.ersjournals.com/content/31/163/210212.full |
| spellingShingle | Kartik Kumar Charles L. Daley David E. Griffith Michael R. Loebinger Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments European Respiratory Review |
| title | Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments |
| title_full | Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments |
| title_fullStr | Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments |
| title_full_unstemmed | Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments |
| title_short | Management of Mycobacterium avium complex and Mycobacterium abscessus pulmonary disease: therapeutic advances and emerging treatments |
| title_sort | management of mycobacterium avium complex and mycobacterium abscessus pulmonary disease therapeutic advances and emerging treatments |
| url | http://err.ersjournals.com/content/31/163/210212.full |
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