Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations
Abstract Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-...
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| Format: | Article |
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Nature Portfolio
2023-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-27376-y |
| _version_ | 1811175856825958400 |
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| author | Ahmed Naceur Alain Hébert Paul Romano Benoit Forget Cornelia Chilian Jean-François Carrier |
| author_facet | Ahmed Naceur Alain Hébert Paul Romano Benoit Forget Cornelia Chilian Jean-François Carrier |
| author_sort | Ahmed Naceur |
| collection | DOAJ |
| description | Abstract Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-art multigroup electron cross sections generation module in NJOY is presented and validated against Lockwood’s calorimetric measurements, EGS-nrc and GEANT-4 for 1–20 MeV unidirectional electron beams. The nuclear-reactor DRAGON-5 solver is upgraded to access the library and solve the Boltzmann–Fokker–Planck (BFP) equation. A variety of heterogeneous radiotherapy and radiosurgery phantom configurations were used for validation purpose. Case studies include a thorax benchmark, that of a typical breast Intra-Operative Radiotherapy and a high-heterogeneity patient-like benchmark. For all beams, $$100\%$$ 100 % of the water voxels satisfied the American Association of Physicists in Medicine accuracy criterion for a BFP-MC dose error below $$2\%$$ 2 % . At least, $$97.0\%$$ 97.0 % of adipose, muscle, bone, lung, tumor and breast voxels satisfied the $$2\%$$ 2 % criterion. The average BFP-MC relative error was about $$0.56\%$$ 0.56 % for all voxels, beams and materials combined. By irradiating homogeneous slabs from $$Z=1$$ Z = 1 (hydrogen) to $$Z=99$$ Z = 99 (einsteinium), we reported performance and defects of the CEPXS mode [US. Sandia National Lab., SAND-89-1685] in ELECTR for the entire periodic table. For all Lockwood’s benchmarks, NJOY-DRAGON dose predictions are within the experimental data precision for $$98\%$$ 98 % of voxels. |
| first_indexed | 2024-04-10T19:43:48Z |
| format | Article |
| id | doaj.art-122bd446e9da48ca80042880dfb79a28 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-10T19:43:48Z |
| publishDate | 2023-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-122bd446e9da48ca80042880dfb79a282023-01-29T12:10:03ZengNature PortfolioScientific Reports2045-23222023-01-0113112110.1038/s41598-023-27376-yFeasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculationsAhmed Naceur0Alain Hébert1Paul Romano2Benoit Forget3Cornelia Chilian4Jean-François Carrier5Department of Engineering Physics, Nuclear Engineering Institute, École PolytechniqueDepartment of Mechanical Engineering, Nuclear Engineering Institute, École PolytechniqueComputational Science Division, Argonne National LaboratoryDepartment of Nuclear Science and Engineering, Massachusetts Institute of TechnologyDepartment of Engineering Physics, Nuclear Engineering Institute, École PolytechniqueCRCHUM, Centre hospitalier de l’Université de MontréalAbstract Legacy nuclear-reactor Boltzmann solvers start clinical deployment as an alternative to Monte Carlo (MC) codes and Fermi–Eyges semiemprical models in radiation oncology treatment planning. Today’s certified clinical solvers are limited to photon beams. In this paper, ELECTR, a state-of-the-art multigroup electron cross sections generation module in NJOY is presented and validated against Lockwood’s calorimetric measurements, EGS-nrc and GEANT-4 for 1–20 MeV unidirectional electron beams. The nuclear-reactor DRAGON-5 solver is upgraded to access the library and solve the Boltzmann–Fokker–Planck (BFP) equation. A variety of heterogeneous radiotherapy and radiosurgery phantom configurations were used for validation purpose. Case studies include a thorax benchmark, that of a typical breast Intra-Operative Radiotherapy and a high-heterogeneity patient-like benchmark. For all beams, $$100\%$$ 100 % of the water voxels satisfied the American Association of Physicists in Medicine accuracy criterion for a BFP-MC dose error below $$2\%$$ 2 % . At least, $$97.0\%$$ 97.0 % of adipose, muscle, bone, lung, tumor and breast voxels satisfied the $$2\%$$ 2 % criterion. The average BFP-MC relative error was about $$0.56\%$$ 0.56 % for all voxels, beams and materials combined. By irradiating homogeneous slabs from $$Z=1$$ Z = 1 (hydrogen) to $$Z=99$$ Z = 99 (einsteinium), we reported performance and defects of the CEPXS mode [US. Sandia National Lab., SAND-89-1685] in ELECTR for the entire periodic table. For all Lockwood’s benchmarks, NJOY-DRAGON dose predictions are within the experimental data precision for $$98\%$$ 98 % of voxels.https://doi.org/10.1038/s41598-023-27376-y |
| spellingShingle | Ahmed Naceur Alain Hébert Paul Romano Benoit Forget Cornelia Chilian Jean-François Carrier Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations Scientific Reports |
| title | Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations |
| title_full | Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations |
| title_fullStr | Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations |
| title_full_unstemmed | Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations |
| title_short | Feasibility of a multigroup Boltzmann–Fokker–Planck solution for electron beam dose calculations |
| title_sort | feasibility of a multigroup boltzmann fokker planck solution for electron beam dose calculations |
| url | https://doi.org/10.1038/s41598-023-27376-y |
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