Xerostomia related to HIV infection /AIDS: a critical review

Introduction: The presence of oral manifestations in HIV positive individuals is quite common. Xerostomia appears as one of the most frequent problems and may lead to a reduction in the quality of life of this population. Objective: This study was a critical review of the relationship between x...

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Main Authors: Adriana Maria Fuzer Grael TINÓS, Sílvia Helena de Carvalho SALES-PERES
Format: Article
Language:English
Published: Universidade Estadual Paulista
Series:Revista de Odontologia da UNESP
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000300214&lng=en&tlng=en
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author Adriana Maria Fuzer Grael TINÓS
Sílvia Helena de Carvalho SALES-PERES
author_facet Adriana Maria Fuzer Grael TINÓS
Sílvia Helena de Carvalho SALES-PERES
author_sort Adriana Maria Fuzer Grael TINÓS
collection DOAJ
description Introduction: The presence of oral manifestations in HIV positive individuals is quite common. Xerostomia appears as one of the most frequent problems and may lead to a reduction in the quality of life of this population. Objective: This study was a critical review of the relationship between xerostomia and HIV infection, to attract the attention of dentists on the importance of dental care to these patients. Material and method: We included articles published between 2000 and 2009, indexed in PUBMED database. The descriptors used were "HIV" and "xerostomia", the exclusion criteria adopted were: the absence of these descriptors associated, non-location of the full-text, articles based on case studies or case series and the absence of the abstract in the database. Result: Based on studies in the review, it can be said that the xerostomia is a common manifestation of HIV infection, predisposing the patient to several other oral problems. Among the risk factors for its occurrence it was reported: low counts of CD4+ T cells, high plasma viral load, the use of some medications and antiretroviral therapy. Conclusion: The HIV/AIDS can change the salivary glands, and were considered important risk factors for the occurrence of xerostomia the presence of didanosine and the drug class which corresponds to protease inhibitors in antiretroviral therapy.
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spelling doaj.art-123355002c1f4264b7b0ecf539c58cc92022-12-21T23:25:43ZengUniversidade Estadual PaulistaRevista de Odontologia da UNESP1807-257743321422210.1590/rou.2014.036S1807-25772014000300214Xerostomia related to HIV infection /AIDS: a critical reviewAdriana Maria Fuzer Grael TINÓSSílvia Helena de Carvalho SALES-PERESIntroduction: The presence of oral manifestations in HIV positive individuals is quite common. Xerostomia appears as one of the most frequent problems and may lead to a reduction in the quality of life of this population. Objective: This study was a critical review of the relationship between xerostomia and HIV infection, to attract the attention of dentists on the importance of dental care to these patients. Material and method: We included articles published between 2000 and 2009, indexed in PUBMED database. The descriptors used were "HIV" and "xerostomia", the exclusion criteria adopted were: the absence of these descriptors associated, non-location of the full-text, articles based on case studies or case series and the absence of the abstract in the database. Result: Based on studies in the review, it can be said that the xerostomia is a common manifestation of HIV infection, predisposing the patient to several other oral problems. Among the risk factors for its occurrence it was reported: low counts of CD4+ T cells, high plasma viral load, the use of some medications and antiretroviral therapy. Conclusion: The HIV/AIDS can change the salivary glands, and were considered important risk factors for the occurrence of xerostomia the presence of didanosine and the drug class which corresponds to protease inhibitors in antiretroviral therapy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000300214&lng=en&tlng=enAIDSHIVsalivaantiretroviral therapy highly activexerostomia
spellingShingle Adriana Maria Fuzer Grael TINÓS
Sílvia Helena de Carvalho SALES-PERES
Xerostomia related to HIV infection /AIDS: a critical review
Revista de Odontologia da UNESP
AIDS
HIV
saliva
antiretroviral therapy highly active
xerostomia
title Xerostomia related to HIV infection /AIDS: a critical review
title_full Xerostomia related to HIV infection /AIDS: a critical review
title_fullStr Xerostomia related to HIV infection /AIDS: a critical review
title_full_unstemmed Xerostomia related to HIV infection /AIDS: a critical review
title_short Xerostomia related to HIV infection /AIDS: a critical review
title_sort xerostomia related to hiv infection aids a critical review
topic AIDS
HIV
saliva
antiretroviral therapy highly active
xerostomia
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-25772014000300214&lng=en&tlng=en
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