Distinct resting-state effective connectivity of large-scale networks in first-episode and recurrent major depression disorder: evidence from the REST-meta-MDD consortium

Distinct resting-state effective connectivity of large-scale networks in first-episode and recurrent major depression disorder: evidence from the REST-meta-MDD consortium

IntroductionPrevious studies have shown disrupted effective connectivity in the large-scale brain networks of individuals with major depressive disorder (MDD). However, it is unclear whether these changes differ between first-episode drug-naive MDD (FEDN-MDD) and recurrent MDD (R-MDD).MethodsThis st...

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Bibliographic Details
Main Authors: Yao Zhu, Tianming Huang, Ruolin Li, Qianrong Yang, Chaoyue Zhao, Ming Yang, Bin Lin, the DIRECT Consortium, Xuzhou Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Neuroscience
Subjects:
major depressive disorder
first-episode and recurrent
resting-state fMRI
brain networks
effective connectivity
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1308551/full

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