The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma

The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma

Abstract Background TP53 is the most frequently mutated gene in human cancers. Previous studies reported that TP53 mutations correlated with poor prognoses in patients with head and neck squamous cell carcinoma (HNSCC). However, the relationship between TP53 mutations and hypopharyngeal squamous cel...

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Bibliographic Details
Main Authors: Go Omura, Mizuo Ando, Yasuhiro Ebihara, Yuki Saito, Kenya Kobayashi, Osamu Fukuoka, Ken Akashi, Masafumi Yoshida, Takahiro Asakage, Tatsuya Yamasoba
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Cancer
Subjects:
TP53 mutation
Hypopharyngeal squamous cell carcinoma
Truncating mutation
Prognosis
Pharyngectomy
Online Access:http://link.springer.com/article/10.1186/s12885-017-3913-1

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