Early interventions to prevent retinal vasculopathy in diabetes: a review

Wendy W Harrison, Vladimir YevseyenkovArizona College of Optometry, Midwestern University, Glendale, AZ, USAAbstract: Diabetic eye disease is a public health concern in all areas of the world as a leading cause of blindness in the working aged to elderly populations. Diabetes damages the lining of t...

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Main Authors: Harrison WW, Yevseyenkov V
Format: Article
Language:English
Published: Dove Medical Press 2015-08-01
Series:Clinical Optometry
Online Access:http://www.dovepress.com/early-interventions-to-prevent-retinal-vasculopathy-in-diabetes-a-revi-peer-reviewed-article-OPTO
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author Harrison WW
Yevseyenkov V
author_facet Harrison WW
Yevseyenkov V
author_sort Harrison WW
collection DOAJ
description Wendy W Harrison, Vladimir YevseyenkovArizona College of Optometry, Midwestern University, Glendale, AZ, USAAbstract: Diabetic eye disease is a public health concern in all areas of the world as a leading cause of blindness in the working aged to elderly populations. Diabetes damages the lining of the microvasculature throughout the body through prolonged exposure to hyperglycemic conditions. The ocular changes are progressive with very little recourse for improvement once damage begins. Current treatments for the eye focus mainly on the late stages of the disease when neovascularization or edema threatens sight. Early interventions for diabetic vasculopathy involve metabolic therapy to improve blood glucose and blood pressure control. Technology improvements have a large part to play in advancing diagnosis of diabetic eye disease. These new technologies offer both structural and functional means for assessment of retinal health. This review focuses on current treatments for diabetic eye disease at all stages with an emphasis on new and early interventions. It also details established and emerging technologies used for earlier detection of diabetic eye disease, which is vital to the development and approval of much needed treatments targeted at earlier stages of diabetic retinopathy. Possible future treatments should be aimed to prevent retinal vasculopathy from progressing. This review will explore current research on this topic and what is needed moving forward.Keywords: diabetes, diabetic retinopathy, vascular disease
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spelling doaj.art-123b3e83e4cd482d90b7bb1b84444a832022-12-22T01:14:59ZengDove Medical PressClinical Optometry1179-27522015-08-012015default718023447Early interventions to prevent retinal vasculopathy in diabetes: a reviewHarrison WWYevseyenkov VWendy W Harrison, Vladimir YevseyenkovArizona College of Optometry, Midwestern University, Glendale, AZ, USAAbstract: Diabetic eye disease is a public health concern in all areas of the world as a leading cause of blindness in the working aged to elderly populations. Diabetes damages the lining of the microvasculature throughout the body through prolonged exposure to hyperglycemic conditions. The ocular changes are progressive with very little recourse for improvement once damage begins. Current treatments for the eye focus mainly on the late stages of the disease when neovascularization or edema threatens sight. Early interventions for diabetic vasculopathy involve metabolic therapy to improve blood glucose and blood pressure control. Technology improvements have a large part to play in advancing diagnosis of diabetic eye disease. These new technologies offer both structural and functional means for assessment of retinal health. This review focuses on current treatments for diabetic eye disease at all stages with an emphasis on new and early interventions. It also details established and emerging technologies used for earlier detection of diabetic eye disease, which is vital to the development and approval of much needed treatments targeted at earlier stages of diabetic retinopathy. Possible future treatments should be aimed to prevent retinal vasculopathy from progressing. This review will explore current research on this topic and what is needed moving forward.Keywords: diabetes, diabetic retinopathy, vascular diseasehttp://www.dovepress.com/early-interventions-to-prevent-retinal-vasculopathy-in-diabetes-a-revi-peer-reviewed-article-OPTO
spellingShingle Harrison WW
Yevseyenkov V
Early interventions to prevent retinal vasculopathy in diabetes: a review
Clinical Optometry
title Early interventions to prevent retinal vasculopathy in diabetes: a review
title_full Early interventions to prevent retinal vasculopathy in diabetes: a review
title_fullStr Early interventions to prevent retinal vasculopathy in diabetes: a review
title_full_unstemmed Early interventions to prevent retinal vasculopathy in diabetes: a review
title_short Early interventions to prevent retinal vasculopathy in diabetes: a review
title_sort early interventions to prevent retinal vasculopathy in diabetes a review
url http://www.dovepress.com/early-interventions-to-prevent-retinal-vasculopathy-in-diabetes-a-revi-peer-reviewed-article-OPTO
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