Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease Fetuses

Objectives: The size of cardiovascular structures in fetuses with congenital heart disease (CHD) is variable, and current reference structures used for comparative purposes are suboptimal: There are no known cardiovascular structures that are reliably normal in size. We sought to evaluate whether th...

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Main Author: Zhongshan Gou, MD, Xinxin Yan, MD, Jianfang Ma, MD, Qi Pan, MD, Zhong Yang, MD, Xuedong Deng. MD
Format: Article
Language:English
Published: Editorial Office of Advanced Ultrasound in Diagnosis and Therapy 2018-08-01
Series:Advanced Ultrasound in Diagnosis and Therapy
Subjects:
Online Access:http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1534732215821-2134597277.pdf
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author Zhongshan Gou, MD, Xinxin Yan, MD, Jianfang Ma, MD, Qi Pan, MD, Zhong Yang, MD, Xuedong Deng. MD
author_facet Zhongshan Gou, MD, Xinxin Yan, MD, Jianfang Ma, MD, Qi Pan, MD, Zhong Yang, MD, Xuedong Deng. MD
author_sort Zhongshan Gou, MD, Xinxin Yan, MD, Jianfang Ma, MD, Qi Pan, MD, Zhong Yang, MD, Xuedong Deng. MD
collection DOAJ
description Objectives: The size of cardiovascular structures in fetuses with congenital heart disease (CHD) is variable, and current reference structures used for comparative purposes are suboptimal: There are no known cardiovascular structures that are reliably normal in size. We sought to evaluate whether the aortic diameter at the diaphragmatic hiatus (ADDH) is affected in CHD. Methods: The ADDH was evaluated by sonography in both study subjects (CHD group, n = 506) and age-matched normal controls (normal group, n = 506). The CHD group was divided into different subgroups according to evident anomalies in the cardiovascular system. ADDH differences between CHD subgroups and their controls were calculated with a paired Student's t-test. Possible sex differences were determined by an unpaired Student's t-test on the whole group. Results: There were no significant differences in the ADDH between all CHD subgroups and age-matched controls (p > 0.05). No difference was found in the ADDH between female and male fetuses (p > 0.05). Conclusion: The ADDH in fetuses with CHD is similar to that in controls. Hence, ratios between size of involved cardiovascular structures and ADDH may be a useful parameter for monitoring fetuses with CHD .
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spelling doaj.art-1240314187114678b7359e661c6f38452022-12-21T19:23:18ZengEditorial Office of Advanced Ultrasound in Diagnosis and TherapyAdvanced Ultrasound in Diagnosis and Therapy2576-25162018-08-012212312710.37015/AUDT.2018.180810Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease FetusesZhongshan Gou, MD, Xinxin Yan, MD, Jianfang Ma, MD, Qi Pan, MD, Zhong Yang, MD, Xuedong Deng. MD0a Department of Ultrasonography;b Department of Pharmacy, Suzhou Hospital Affiliated to Nanjing Medical University, Suzhou, ChinaObjectives: The size of cardiovascular structures in fetuses with congenital heart disease (CHD) is variable, and current reference structures used for comparative purposes are suboptimal: There are no known cardiovascular structures that are reliably normal in size. We sought to evaluate whether the aortic diameter at the diaphragmatic hiatus (ADDH) is affected in CHD. Methods: The ADDH was evaluated by sonography in both study subjects (CHD group, n = 506) and age-matched normal controls (normal group, n = 506). The CHD group was divided into different subgroups according to evident anomalies in the cardiovascular system. ADDH differences between CHD subgroups and their controls were calculated with a paired Student's t-test. Possible sex differences were determined by an unpaired Student's t-test on the whole group. Results: There were no significant differences in the ADDH between all CHD subgroups and age-matched controls (p > 0.05). No difference was found in the ADDH between female and male fetuses (p > 0.05). Conclusion: The ADDH in fetuses with CHD is similar to that in controls. Hence, ratios between size of involved cardiovascular structures and ADDH may be a useful parameter for monitoring fetuses with CHD .http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1534732215821-2134597277.pdf|ultrasound|aortic diameter|diaphragmatic hiatus|congenital heart disease
spellingShingle Zhongshan Gou, MD, Xinxin Yan, MD, Jianfang Ma, MD, Qi Pan, MD, Zhong Yang, MD, Xuedong Deng. MD
Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease Fetuses
Advanced Ultrasound in Diagnosis and Therapy
|ultrasound|aortic diameter|diaphragmatic hiatus|congenital heart disease
title Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease Fetuses
title_full Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease Fetuses
title_fullStr Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease Fetuses
title_full_unstemmed Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease Fetuses
title_short Ultrasound Measurement of Aortic Diameter at the Diaphragmatic Hiatus in Normal and Congenital Heart Disease Fetuses
title_sort ultrasound measurement of aortic diameter at the diaphragmatic hiatus in normal and congenital heart disease fetuses
topic |ultrasound|aortic diameter|diaphragmatic hiatus|congenital heart disease
url http://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1534732215821-2134597277.pdf
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