Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit

Functional Analysis of the GPI Transamidase Complex by Screening for Amino Acid Mutations in Each Subunit

Glycosylphosphatidylinositol (GPI) anchor modification is a posttranslational modification of proteins that has been conserved in eukaryotes. The biosynthesis and transfer of GPI to proteins are carried out in the endoplasmic reticulum. Attachment of GPI to proteins is mediated by the GPI-transamida...

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Bibliographic Details
Main Authors: Si-Si Liu, Fei Jin, Yi-Shi Liu, Yoshiko Murakami, Yukihiko Sugita, Takayuki Kato, Xiao-Dong Gao, Taroh Kinoshita, Motoyuki Hattori, Morihisa Fujita
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Molecules
Subjects:
glyco-diosgenin
GPI-anchored proteins
GPI-transamidase
protein purification
single particle
Online Access:https://www.mdpi.com/1420-3049/26/18/5462

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