HDAC4 depletion ameliorates IL‐13‐triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF‐κB signaling

HDAC4 depletion ameliorates IL‐13‐triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF‐κB signaling

Abstract Introduction Allergic rhinitis (AR) is frequently known as a chronic respiratory disease with a global high prevalence. The pivotal roles of histone deacetylase 4 (HDAC4) in multiple human diseases have been underlined by numerous studies. Nevertheless, whether HDAC4 is implicated in AR rem...

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Bibliographic Details
Main Authors: Hangyu Xu, Lingjun Wang, Huaqun Chen, Hefei Cai
Format: Article
Language:English
Published: Wiley 2022-11-01
Series:Immunity, Inflammation and Disease
Subjects:
allergic rhinitis
HDAC4
inflammatory response
MUC5AC
SIRT1/NF‐κB signaling
Online Access:https://doi.org/10.1002/iid3.692

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