Genus Curcuma: chemical and ethnopharmacological role in aging process
Abstract Aging or senescence is part of human life development with many effects on the physical, mental, and physiological aspects which may lead to age-related deterioration in many organs. Genus Curcuma family Zingieraceae represents one of the well-studied and medically important genera with mor...
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Complementary Medicine and Therapies |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12906-023-04317-w |
| _version_ | 1827382386468323328 |
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| author | Esraa A. Elhawary Ashaimaa Y. Moussa Abdel Nasser B. Singab |
| author_facet | Esraa A. Elhawary Ashaimaa Y. Moussa Abdel Nasser B. Singab |
| author_sort | Esraa A. Elhawary |
| collection | DOAJ |
| description | Abstract Aging or senescence is part of human life development with many effects on the physical, mental, and physiological aspects which may lead to age-related deterioration in many organs. Genus Curcuma family Zingieraceae represents one of the well-studied and medically important genera with more than eighty species. The genus is reported to contain different classes of biologically active compounds that are mainly presented in diphenylheptanoids, diphenylpentanoids, diphenylalkanoids, phenylpropene derivatives, alkaloids, flavonoids, chromones, terpenoids, phenolic acids and volatile constituents. Rhizomes and roots of such species are rich with main phytoconstituents viz. curcumin, demethoxycurcumin and bis-demethoxycurcumin. A wide variety of biological activities were demonstrated for different extracts and essential oils of genus Curcuma members including antioxidant, anti-inflammatory, cytotoxic and neuroprotective. Thus, making them as an excellent safe source for nutraceutical products and as a continuous promising area of research on lead compounds that may help in the slowing down of the aging process especially the neurologic and mental deterioration that are usually experienced upon aging. In this review different species of the genus Curcuma were summarized with their phytochemical and biological activities highlighting their role as antiaging agents. The data were collected from different search engines viz. Pubmed®, Google Scholar®, Scopus® and Web of Science® limiting the search to the period between 2003 up till now. |
| first_indexed | 2024-03-08T14:18:48Z |
| format | Article |
| id | doaj.art-1249e277b43946508c0c2258dfebcb64 |
| institution | Directory Open Access Journal |
| issn | 2662-7671 |
| language | English |
| last_indexed | 2024-03-08T14:18:48Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Complementary Medicine and Therapies |
| spelling | doaj.art-1249e277b43946508c0c2258dfebcb642024-01-14T12:11:48ZengBMCBMC Complementary Medicine and Therapies2662-76712024-01-0124111710.1186/s12906-023-04317-wGenus Curcuma: chemical and ethnopharmacological role in aging processEsraa A. Elhawary0Ashaimaa Y. Moussa1Abdel Nasser B. Singab2Department of Pharmacognosy, Faculty of Pharmacy, Ain Shams UniversityDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams UniversityDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams UniversityAbstract Aging or senescence is part of human life development with many effects on the physical, mental, and physiological aspects which may lead to age-related deterioration in many organs. Genus Curcuma family Zingieraceae represents one of the well-studied and medically important genera with more than eighty species. The genus is reported to contain different classes of biologically active compounds that are mainly presented in diphenylheptanoids, diphenylpentanoids, diphenylalkanoids, phenylpropene derivatives, alkaloids, flavonoids, chromones, terpenoids, phenolic acids and volatile constituents. Rhizomes and roots of such species are rich with main phytoconstituents viz. curcumin, demethoxycurcumin and bis-demethoxycurcumin. A wide variety of biological activities were demonstrated for different extracts and essential oils of genus Curcuma members including antioxidant, anti-inflammatory, cytotoxic and neuroprotective. Thus, making them as an excellent safe source for nutraceutical products and as a continuous promising area of research on lead compounds that may help in the slowing down of the aging process especially the neurologic and mental deterioration that are usually experienced upon aging. In this review different species of the genus Curcuma were summarized with their phytochemical and biological activities highlighting their role as antiaging agents. The data were collected from different search engines viz. Pubmed®, Google Scholar®, Scopus® and Web of Science® limiting the search to the period between 2003 up till now.https://doi.org/10.1186/s12906-023-04317-wCurcumaZingiberaceaeAnti-agingEthnobotanyNeuroprotective |
| spellingShingle | Esraa A. Elhawary Ashaimaa Y. Moussa Abdel Nasser B. Singab Genus Curcuma: chemical and ethnopharmacological role in aging process BMC Complementary Medicine and Therapies Curcuma Zingiberaceae Anti-aging Ethnobotany Neuroprotective |
| title | Genus Curcuma: chemical and ethnopharmacological role in aging process |
| title_full | Genus Curcuma: chemical and ethnopharmacological role in aging process |
| title_fullStr | Genus Curcuma: chemical and ethnopharmacological role in aging process |
| title_full_unstemmed | Genus Curcuma: chemical and ethnopharmacological role in aging process |
| title_short | Genus Curcuma: chemical and ethnopharmacological role in aging process |
| title_sort | genus curcuma chemical and ethnopharmacological role in aging process |
| topic | Curcuma Zingiberaceae Anti-aging Ethnobotany Neuroprotective |
| url | https://doi.org/10.1186/s12906-023-04317-w |
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