The role of cGAS-STING signaling in pulmonary fibrosis and its therapeutic potential

The role of cGAS-STING signaling in pulmonary fibrosis and its therapeutic potential

Pulmonary fibrosis is a progressive and ultimately fatal lung disease, exhibiting the excessive production of extracellular matrix and aberrant activation of fibroblast. While Pirfenidone and Nintedanib are FDA-approved drugs that can slow down the progression of pulmonary fibrosis, they are unable...

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Bibliographic Details
Main Authors: Jing Zhang, Lanlan Zhang, Yutian Chen, Xiaobin Fang, Bo Li, Chunheng Mo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
pulmonary fibrosis
cGAS-STING
signaling pathway
inhibitors
therapeutic potential
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273248/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1273248/full

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