Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark
Abstract Objective Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. geni...
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| Format: | Article |
| Language: | English |
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BMC
2017-09-01
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| Series: | BMC Research Notes |
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| Online Access: | http://link.springer.com/article/10.1186/s13104-017-2776-5 |
| _version_ | 1828498128754442240 |
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| author | Anne Marie Rosendahl Madsen Kristina Thorsteinsson Anne-Mette Lebech Merete Storgaard Terese L. Katzenstein Frederikke F. Rönsholt Isik Somuncu Johansen Gitte Pedersen Lars Noerregaard Nielsen Aase Bengaard Andersen Jørgen Skov Jensen |
| author_facet | Anne Marie Rosendahl Madsen Kristina Thorsteinsson Anne-Mette Lebech Merete Storgaard Terese L. Katzenstein Frederikke F. Rönsholt Isik Somuncu Johansen Gitte Pedersen Lars Noerregaard Nielsen Aase Bengaard Andersen Jørgen Skov Jensen |
| author_sort | Anne Marie Rosendahl Madsen |
| collection | DOAJ |
| description | Abstract Objective Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. genitalium has been suggested as part of HIV prevention strategies. The objective of this study was to determine the prevalence of M. genitalium in women living with HIV (WLWH) in Denmark, and to compare the result with data on symptoms from the lower abdomen, sexual habits and immune status. 234 women, recruited from Danish HIV centres as part of a larger observational study on aspects of living with HIV as a woman (the SHADE study), were included. Results We tested cervical samples for M. genitalium by specific PCR. We found three samples positive (1.3%). The women were between 30 and 50 years old, all were of Asian origin, sexually active, and on antiretroviral treatment with supressed HIV RNA and CD4 count >350 cells/µL. None reported symptoms from the lower abdomen. The prevalence of M. genitalium infection in WLWH in Denmark is low, thus systematic screening for M. genitalium in this group does not seem relevant. |
| first_indexed | 2024-12-11T13:00:16Z |
| format | Article |
| id | doaj.art-124b10b5b08748f284ce0274d815f5c1 |
| institution | Directory Open Access Journal |
| issn | 1756-0500 |
| language | English |
| last_indexed | 2024-12-11T13:00:16Z |
| publishDate | 2017-09-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Research Notes |
| spelling | doaj.art-124b10b5b08748f284ce0274d815f5c12022-12-22T01:06:28ZengBMCBMC Research Notes1756-05002017-09-011011510.1186/s13104-017-2776-5Prevalence and significance of Mycoplasma genitalium in women living with HIV in DenmarkAnne Marie Rosendahl Madsen0Kristina Thorsteinsson1Anne-Mette Lebech2Merete Storgaard3Terese L. Katzenstein4Frederikke F. Rönsholt5Isik Somuncu Johansen6Gitte Pedersen7Lars Noerregaard Nielsen8Aase Bengaard Andersen9Jørgen Skov Jensen10Department of Clinical Microbiology, Odense University HospitalDepartment of Infectious Diseases, Copenhagen University HospitalDepartment of Infectious Diseases, Copenhagen University HospitalDepartment of Infectious Diseases, Aarhus University HospitalDepartment of Infectious Diseases, Copenhagen University Hospital, RigshospitaletDepartment of Infectious Diseases, Copenhagen University Hospital, RigshospitaletDepartment of Infectious Diseases, Odense University HospitalDepartment of Infectious Diseases, Aalborg University HospitalDepartment of Infectious Diseases, Hillerød HospitalDepartment of Infectious Diseases, Copenhagen University Hospital, RigshospitaletStatens Serum InstitutAbstract Objective Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. genitalium has been suggested as part of HIV prevention strategies. The objective of this study was to determine the prevalence of M. genitalium in women living with HIV (WLWH) in Denmark, and to compare the result with data on symptoms from the lower abdomen, sexual habits and immune status. 234 women, recruited from Danish HIV centres as part of a larger observational study on aspects of living with HIV as a woman (the SHADE study), were included. Results We tested cervical samples for M. genitalium by specific PCR. We found three samples positive (1.3%). The women were between 30 and 50 years old, all were of Asian origin, sexually active, and on antiretroviral treatment with supressed HIV RNA and CD4 count >350 cells/µL. None reported symptoms from the lower abdomen. The prevalence of M. genitalium infection in WLWH in Denmark is low, thus systematic screening for M. genitalium in this group does not seem relevant.http://link.springer.com/article/10.1186/s13104-017-2776-5Mycoplasma genitaliumHIVWomen living with HIVSexually transmitted diseases |
| spellingShingle | Anne Marie Rosendahl Madsen Kristina Thorsteinsson Anne-Mette Lebech Merete Storgaard Terese L. Katzenstein Frederikke F. Rönsholt Isik Somuncu Johansen Gitte Pedersen Lars Noerregaard Nielsen Aase Bengaard Andersen Jørgen Skov Jensen Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark BMC Research Notes Mycoplasma genitalium HIV Women living with HIV Sexually transmitted diseases |
| title | Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark |
| title_full | Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark |
| title_fullStr | Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark |
| title_full_unstemmed | Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark |
| title_short | Prevalence and significance of Mycoplasma genitalium in women living with HIV in Denmark |
| title_sort | prevalence and significance of mycoplasma genitalium in women living with hiv in denmark |
| topic | Mycoplasma genitalium HIV Women living with HIV Sexually transmitted diseases |
| url | http://link.springer.com/article/10.1186/s13104-017-2776-5 |
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