Morphological and electrophysiological changes in intratelencephalic-type pyramidal neurons in the motor cortex of a rat model of levodopa-induced dyskinesia

Morphological and electrophysiological changes in intratelencephalic-type pyramidal neurons in the motor cortex of a rat model of levodopa-induced dyskinesia

Levodopa-induced dyskinesia (LID) is a major complication of long-term dopamine replacement therapy for Parkinson's disease, and becomes increasingly problematic in the advanced stage of the disease. Although the cause of LID still remains unclear, there is accumulating evidence from animal exp...

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Bibliographic Details
Main Authors: Tatsuya Ueno, Junko Yamada, Haruo Nishijima, Akira Arai, Keisuke Migita, Masayuki Baba, Shinya Ueno, Masahiko Tomiyama
Format: Article
Language:English
Published: Elsevier 2014-04-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Dyskinesia
Levodopa
Motor cortex
Spine
Plasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113003586

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