Design and optimization of ganciclovir solid dispersion for improving its bioavailability

Design and optimization of ganciclovir solid dispersion for improving its bioavailability

Development of new approaches for oral delivery of an existing antiviral drug aimed to enhance its permeability and hence bioavailability. Ganciclovir (GC) is an antiviral drug that belongs to class III in biopharmaceutical classification. The encapsulation of poorly absorbed drugs within nanosized...

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Bibliographic Details
Main Authors: Dalia A. Gaber, Manar A. Alnwiser, Nadia L. Alotaibi, Rawan A. Almutairi, Sumaih S. Alsaeed, Siham A. Abdoun, Amal M. Alsubaiyel
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Drug Delivery
Subjects:
Gancyclovir
cyclodextrin
shellac
solid dispersion
nanoparticles
factorial design
Online Access:https://www.tandfonline.com/doi/10.1080/10717544.2022.2083723

Internet

https://www.tandfonline.com/doi/10.1080/10717544.2022.2083723

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