REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF)
In the work were used: 15-16 and 20-21 daily embryos of rats, newborns, 1 45 daily rats Wistar males. A morphometric analysis of the myocardial parenchyma of the complex left ventricle + interventricular septum (LV + IVF) was performed. It was established that in the process of prenatal and postna...
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| Format: | Article |
| Language: | English |
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Ukrainian Medical Stomatological Academy
2019-04-01
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| Series: | Вісник проблем біології і медицини |
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| Online Access: | https://vpbm.com.ua/upload/2019-2-1/15-min.pdf |
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| author | Zagoruóko óko Yu. V. Zagoruóko óko G. E. Martsinovsky V. P. Filatova V. L. |
| author_facet | Zagoruóko óko Yu. V. Zagoruóko óko G. E. Martsinovsky V. P. Filatova V. L. |
| author_sort | Zagoruóko óko Yu. V. |
| collection | DOAJ |
| description | In the work were used: 15-16 and 20-21 daily embryos of rats, newborns, 1 45 daily rats Wistar males.
A morphometric analysis of the myocardial parenchyma of the complex left ventricle + interventricular septum
(LV + IVF) was performed. It was established that in the process of prenatal and postnatal cardiomyogenesis (15
days before and 45 days after) birth, the total number of CMC (? cmc = N1-ñ 1st cmc + N2-ñ cmc) in the parenchyma
(LV + IVF) increases by 4,34 times (from 0.35 to 1.52) x 107 cmc. During the period of embryonic cardiomyogenesis
(15-21) days, the values of L cmc increase by 2 times (from 0.35 to 0.74) x 107
cmc. In the process of postnatal
cardiomyogenesis, in the time interval (newborns 15 daily rats), the volume of values cmc also increases by 2 times
(from 0.77 to 1.52) x 107
cmc. In the time interval (1545) days, the total number of cmc does not change ? cmc ?
const ? (1.51 ± 0.02) x 107
cmc. During the embryonic period of cardiomyogenesis continuous proliferation of cmc
occurs with a maximum speed of 3.75 x 104
cmc/h or 625 cmc/min in the myocardial parenchyma of the newborn
rat pups. After birth a significant decrease in the rate of proliferative processes in the myocardial parenchyma is
observed. at t > 15 days, ?N cmc/day > 0. The formation of the 2nd cmc population in the myocardium of the
complex (LV + IVF) begins from the 19th day of embryogenesis in rats. In the process of cardiomyogenesis (18 days
before and 15 days after) the birth of rat pups as a result of polyploidy the number of 2nd cmc in the parenchyma
(LV + IVF) increases 1000 times! (from 0.00144 to 1.44) x 107
cmc. In the time interval tº (15 45) days the digital
values of the index N 2cmc ? const ? 1.44 x 107
cmc. Therefore, after the completion of the postnatal period of
cardiomyogenesis, the number of 2nd cmc does not change and amounts to ? 94 95% of the total number of myocytes in the myocardial parenchyma of the complex (LV + IVF). The most active polyploidy process of cmc occurs
within 5 days after the birth of rat pups. The maximum speed of polyploidy of cmc is determined on the 5th day and
is equal to 73 x 103
cmc/h or 1215 cmc/min. |
| first_indexed | 2024-12-18T17:08:34Z |
| format | Article |
| id | doaj.art-125a18f957e849d2825a3964c1c15ee2 |
| institution | Directory Open Access Journal |
| issn | 2077-4214 2523-4110 |
| language | English |
| last_indexed | 2024-12-18T17:08:34Z |
| publishDate | 2019-04-01 |
| publisher | Ukrainian Medical Stomatological Academy |
| record_format | Article |
| series | Вісник проблем біології і медицини |
| spelling | doaj.art-125a18f957e849d2825a3964c1c15ee22022-12-21T21:00:17ZengUkrainian Medical Stomatological AcademyВісник проблем біології і медицини2077-42142523-41102019-04-012170-510.29254/2077-4214-2019-1-2-149-70-752077-4214-2019-1-2-149-70-75REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF)Zagoruóko óko Yu. V.0Zagoruóko óko G. E.1Martsinovsky V. P.2Filatova V. L.3 University Name University Name University Name University Name In the work were used: 15-16 and 20-21 daily embryos of rats, newborns, 1 45 daily rats Wistar males. A morphometric analysis of the myocardial parenchyma of the complex left ventricle + interventricular septum (LV + IVF) was performed. It was established that in the process of prenatal and postnatal cardiomyogenesis (15 days before and 45 days after) birth, the total number of CMC (? cmc = N1-ñ 1st cmc + N2-ñ cmc) in the parenchyma (LV + IVF) increases by 4,34 times (from 0.35 to 1.52) x 107 cmc. During the period of embryonic cardiomyogenesis (15-21) days, the values of L cmc increase by 2 times (from 0.35 to 0.74) x 107 cmc. In the process of postnatal cardiomyogenesis, in the time interval (newborns 15 daily rats), the volume of values cmc also increases by 2 times (from 0.77 to 1.52) x 107 cmc. In the time interval (1545) days, the total number of cmc does not change ? cmc ? const ? (1.51 ± 0.02) x 107 cmc. During the embryonic period of cardiomyogenesis continuous proliferation of cmc occurs with a maximum speed of 3.75 x 104 cmc/h or 625 cmc/min in the myocardial parenchyma of the newborn rat pups. After birth a significant decrease in the rate of proliferative processes in the myocardial parenchyma is observed. at t > 15 days, ?N cmc/day > 0. The formation of the 2nd cmc population in the myocardium of the complex (LV + IVF) begins from the 19th day of embryogenesis in rats. In the process of cardiomyogenesis (18 days before and 15 days after) the birth of rat pups as a result of polyploidy the number of 2nd cmc in the parenchyma (LV + IVF) increases 1000 times! (from 0.00144 to 1.44) x 107 cmc. In the time interval tº (15 45) days the digital values of the index N 2cmc ? const ? 1.44 x 107 cmc. Therefore, after the completion of the postnatal period of cardiomyogenesis, the number of 2nd cmc does not change and amounts to ? 94 95% of the total number of myocytes in the myocardial parenchyma of the complex (LV + IVF). The most active polyploidy process of cmc occurs within 5 days after the birth of rat pups. The maximum speed of polyploidy of cmc is determined on the 5th day and is equal to 73 x 103 cmc/h or 1215 cmc/min. https://vpbm.com.ua/upload/2019-2-1/15-min.pdf ratscardiomyogenesisproliferationpolyploidycardiomyocytesleft ventricle + interventricular septum. |
| spellingShingle | Zagoruóko óko Yu. V. Zagoruóko óko G. E. Martsinovsky V. P. Filatova V. L. REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF) Вісник проблем біології і медицини rats cardiomyogenesis proliferation polyploidy cardiomyocytes left ventricle + interventricular septum. |
| title | REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF) |
| title_full | REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF) |
| title_fullStr | REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF) |
| title_full_unstemmed | REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF) |
| title_short | REGULARITIES OF CARDIOMYOGENESIS IN WISTAR RATS: CARDIOMYOCYTES NUMBER OF GROWTH AND FORMATION OF PUBLICATION OF DUAL MYOCYTES IN THE COMPLEX MYOCARDIUM (LV + IVF) |
| title_sort | regularities of cardiomyogenesis in wistar rats cardiomyocytes number of growth and formation of publication of dual myocytes in the complex myocardium lv ivf |
| topic | rats cardiomyogenesis proliferation polyploidy cardiomyocytes left ventricle + interventricular septum. |
| url | https://vpbm.com.ua/upload/2019-2-1/15-min.pdf |
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