Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in China
Background The gender differences in demographic and clinical characteristics were examined in patients with hepatitis B virus (HBV)-related liver diseases. Methods Overall, 634 patients (44.7 ± 13.8 years) were consecutively included. Data of demographic and clinical characteristics were collected...
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PeerJ Inc.
2022-08-01
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| Online Access: | https://peerj.com/articles/13828.pdf |
| _version_ | 1827609131224137728 |
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| author | Mei Liu Lu Li Jing Zhao Gabor S. Ungvari Chee H. Ng Zhongping Duan Su-Jun Zheng Yu-Tao Xiang |
| author_facet | Mei Liu Lu Li Jing Zhao Gabor S. Ungvari Chee H. Ng Zhongping Duan Su-Jun Zheng Yu-Tao Xiang |
| author_sort | Mei Liu |
| collection | DOAJ |
| description | Background The gender differences in demographic and clinical characteristics were examined in patients with hepatitis B virus (HBV)-related liver diseases. Methods Overall, 634 patients (44.7 ± 13.8 years) were consecutively included. Data of demographic and clinical characteristics were collected during an assessment interview. Comparisons between male and female patients in terms of demographic and clinical data were carried out using univariate analyses. The independent associations between the demographic and clinical variables and gender were examined with either logistic regression or analysis of covariance as appropriate. Results The study sample consisted of 452 male and 182 female patients. Multiple logistic regression analyses revealed that being employed (OR = 3.4), personal monthly income <3,000 yuan (OR = 0.3), being current alcohol users (OR = 6.4), Cirrhosis (OR = 5.9), Hepatocellular Carcinoma (HCC) (OR = 8.5) and having less severe insomnia (OR = 0.6) were independently associated with male gender. The analysis of covariance revealed that after controlling for other potential confounding variables, later onset of HBV-related diseases (F = 4.5, p = 0.03) and older age (F = 6.7, p = 0.009) were independently associated with male gender. Conclusions Given the significant clinical differences in male and female patients with HBV-related liver diseases, more attention should be given to gender-specific treatment and prevention for this population. |
| first_indexed | 2024-03-09T07:26:50Z |
| format | Article |
| id | doaj.art-125ca3a1a6b0460294d1256173f2b30c |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T07:26:50Z |
| publishDate | 2022-08-01 |
| publisher | PeerJ Inc. |
| record_format | Article |
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| spelling | doaj.art-125ca3a1a6b0460294d1256173f2b30c2023-12-03T06:53:10ZengPeerJ Inc.PeerJ2167-83592022-08-0110e1382810.7717/peerj.13828Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in ChinaMei Liu0Lu Li1Jing Zhao2Gabor S. Ungvari3Chee H. Ng4Zhongping Duan5Su-Jun Zheng6Yu-Tao Xiang7Artificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, ChinaThe Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital), Guangzhou, ChinaArtificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, ChinaUniversity of Notre Dame Australia, Fremantle, AustraliaDepartment of Psychiatry, The Melbourne Clinic and St Vincent’s Hospital, University of Melbourne, Richmond, Victoria, AustraliaArtificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, ChinaArtificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, ChinaCentre for Cognitive and Brain Sciences, University of Macau, Macao SAR, ChinaBackground The gender differences in demographic and clinical characteristics were examined in patients with hepatitis B virus (HBV)-related liver diseases. Methods Overall, 634 patients (44.7 ± 13.8 years) were consecutively included. Data of demographic and clinical characteristics were collected during an assessment interview. Comparisons between male and female patients in terms of demographic and clinical data were carried out using univariate analyses. The independent associations between the demographic and clinical variables and gender were examined with either logistic regression or analysis of covariance as appropriate. Results The study sample consisted of 452 male and 182 female patients. Multiple logistic regression analyses revealed that being employed (OR = 3.4), personal monthly income <3,000 yuan (OR = 0.3), being current alcohol users (OR = 6.4), Cirrhosis (OR = 5.9), Hepatocellular Carcinoma (HCC) (OR = 8.5) and having less severe insomnia (OR = 0.6) were independently associated with male gender. The analysis of covariance revealed that after controlling for other potential confounding variables, later onset of HBV-related diseases (F = 4.5, p = 0.03) and older age (F = 6.7, p = 0.009) were independently associated with male gender. Conclusions Given the significant clinical differences in male and female patients with HBV-related liver diseases, more attention should be given to gender-specific treatment and prevention for this population.https://peerj.com/articles/13828.pdfGender differenceHBV-related liver diseasesDemographic |
| spellingShingle | Mei Liu Lu Li Jing Zhao Gabor S. Ungvari Chee H. Ng Zhongping Duan Su-Jun Zheng Yu-Tao Xiang Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in China PeerJ Gender difference HBV-related liver diseases Demographic |
| title | Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in China |
| title_full | Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in China |
| title_fullStr | Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in China |
| title_full_unstemmed | Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in China |
| title_short | Gender differences in demographic and clinical characteristics in patients with HBV-related liver diseases in China |
| title_sort | gender differences in demographic and clinical characteristics in patients with hbv related liver diseases in china |
| topic | Gender difference HBV-related liver diseases Demographic |
| url | https://peerj.com/articles/13828.pdf |
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