EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS

The adenohypophysis produces among other hormones prolactin, which plays an important role in reproduction, especially on the mammary glands and lactation of mammals. Prolactin is tonically controlled by tufo-infundibular dopamine, but several studies indicate that prolactin secretion is altered by...

Full description

Bibliographic Details
Main Authors: C. D. C. Sanches, B. S. Moretti, R. C. A. Berber, E. E. T. S. Hucke
Format: Article
Language:English
Published: Universidade Federal de Rondonópolis 2018-04-01
Series:Scientific Electronic Archives
Subjects:
Online Access:http://www.seasinop.com.br/revista/index.php?journal=SEA&page=article&op=view&path%5B%5D=458&path%5B%5D=pdf
_version_ 1819161381194170368
author C. D. C. Sanches
B. S. Moretti
R. C. A. Berber
E. E. T. S. Hucke
author_facet C. D. C. Sanches
B. S. Moretti
R. C. A. Berber
E. E. T. S. Hucke
author_sort C. D. C. Sanches
collection DOAJ
description The adenohypophysis produces among other hormones prolactin, which plays an important role in reproduction, especially on the mammary glands and lactation of mammals. Prolactin is tonically controlled by tufo-infundibular dopamine, but several studies indicate that prolactin secretion is altered by the action of glucocorticoids and, therefore, is related to stress. However, the exact contribution of corticosteroids in the control of prolactin secretion is poorly understood. On the other hand, it is also known that reproductive experience can modify prolactin secretion by adenohypophysis. Thus, the present study aims to study the hormonal relationships of the hypothalamic-pituitary-adrenal axis, in particular, the glucocorticoid relationship on prolactin secretion as a function of the reproductive experience in females during lactation. The results show that reproductive experience may be a factor modifying the sensitivity of the neuroendocrine response of prolactin secretion to glucocorticoids. However, more studies are needed to understand the possible mechanisms involved, as well as possible modifications in this response as a function of the reproductive status of the females.
first_indexed 2024-12-22T17:11:26Z
format Article
id doaj.art-125ca7bb490e4f2ea408ff7de21248ad
institution Directory Open Access Journal
issn 2316-9281
2316-9281
language English
last_indexed 2024-12-22T17:11:26Z
publishDate 2018-04-01
publisher Universidade Federal de Rondonópolis
record_format Article
series Scientific Electronic Archives
spelling doaj.art-125ca7bb490e4f2ea408ff7de21248ad2022-12-21T18:19:04ZengUniversidade Federal de RondonópolisScientific Electronic Archives2316-92812316-92812018-04-01112111118EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATSC. D. C. SanchesB. S. MorettiR. C. A. BerberE. E. T. S. HuckeThe adenohypophysis produces among other hormones prolactin, which plays an important role in reproduction, especially on the mammary glands and lactation of mammals. Prolactin is tonically controlled by tufo-infundibular dopamine, but several studies indicate that prolactin secretion is altered by the action of glucocorticoids and, therefore, is related to stress. However, the exact contribution of corticosteroids in the control of prolactin secretion is poorly understood. On the other hand, it is also known that reproductive experience can modify prolactin secretion by adenohypophysis. Thus, the present study aims to study the hormonal relationships of the hypothalamic-pituitary-adrenal axis, in particular, the glucocorticoid relationship on prolactin secretion as a function of the reproductive experience in females during lactation. The results show that reproductive experience may be a factor modifying the sensitivity of the neuroendocrine response of prolactin secretion to glucocorticoids. However, more studies are needed to understand the possible mechanisms involved, as well as possible modifications in this response as a function of the reproductive status of the females.http://www.seasinop.com.br/revista/index.php?journal=SEA&page=article&op=view&path%5B%5D=458&path%5B%5D=pdfProlactinaadrenalectomiacorticosteróidesdopaminalactação
spellingShingle C. D. C. Sanches
B. S. Moretti
R. C. A. Berber
E. E. T. S. Hucke
EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS
Scientific Electronic Archives
Prolactina
adrenalectomia
corticosteróides
dopamina
lactação
title EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS
title_full EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS
title_fullStr EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS
title_full_unstemmed EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS
title_short EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS
title_sort effect of adrenalectomy on prolactin secretion in primiparous and multiparous lactating rats
topic Prolactina
adrenalectomia
corticosteróides
dopamina
lactação
url http://www.seasinop.com.br/revista/index.php?journal=SEA&page=article&op=view&path%5B%5D=458&path%5B%5D=pdf
work_keys_str_mv AT cdcsanches effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats
AT bsmoretti effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats
AT rcaberber effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats
AT eetshucke effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats