EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS
The adenohypophysis produces among other hormones prolactin, which plays an important role in reproduction, especially on the mammary glands and lactation of mammals. Prolactin is tonically controlled by tufo-infundibular dopamine, but several studies indicate that prolactin secretion is altered by...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Universidade Federal de Rondonópolis
2018-04-01
|
Series: | Scientific Electronic Archives |
Subjects: | |
Online Access: | http://www.seasinop.com.br/revista/index.php?journal=SEA&page=article&op=view&path%5B%5D=458&path%5B%5D=pdf |
_version_ | 1819161381194170368 |
---|---|
author | C. D. C. Sanches B. S. Moretti R. C. A. Berber E. E. T. S. Hucke |
author_facet | C. D. C. Sanches B. S. Moretti R. C. A. Berber E. E. T. S. Hucke |
author_sort | C. D. C. Sanches |
collection | DOAJ |
description | The adenohypophysis produces among other hormones prolactin, which plays an important role in reproduction, especially on the mammary glands and lactation of mammals. Prolactin is tonically controlled by tufo-infundibular dopamine, but several studies indicate that prolactin secretion is altered by the action of glucocorticoids and, therefore, is related to stress. However, the exact contribution of corticosteroids in the control of prolactin secretion is poorly understood. On the other hand, it is also known that reproductive experience can modify prolactin secretion by adenohypophysis. Thus, the present study aims to study the hormonal relationships of the hypothalamic-pituitary-adrenal axis, in particular, the glucocorticoid relationship on prolactin secretion as a function of the reproductive experience in females during lactation. The results show that reproductive experience may be a factor modifying the sensitivity of the neuroendocrine response of prolactin secretion to glucocorticoids. However, more studies are needed to understand the possible mechanisms involved, as well as possible modifications in this response as a function of the reproductive status of the females. |
first_indexed | 2024-12-22T17:11:26Z |
format | Article |
id | doaj.art-125ca7bb490e4f2ea408ff7de21248ad |
institution | Directory Open Access Journal |
issn | 2316-9281 2316-9281 |
language | English |
last_indexed | 2024-12-22T17:11:26Z |
publishDate | 2018-04-01 |
publisher | Universidade Federal de Rondonópolis |
record_format | Article |
series | Scientific Electronic Archives |
spelling | doaj.art-125ca7bb490e4f2ea408ff7de21248ad2022-12-21T18:19:04ZengUniversidade Federal de RondonópolisScientific Electronic Archives2316-92812316-92812018-04-01112111118EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATSC. D. C. SanchesB. S. MorettiR. C. A. BerberE. E. T. S. HuckeThe adenohypophysis produces among other hormones prolactin, which plays an important role in reproduction, especially on the mammary glands and lactation of mammals. Prolactin is tonically controlled by tufo-infundibular dopamine, but several studies indicate that prolactin secretion is altered by the action of glucocorticoids and, therefore, is related to stress. However, the exact contribution of corticosteroids in the control of prolactin secretion is poorly understood. On the other hand, it is also known that reproductive experience can modify prolactin secretion by adenohypophysis. Thus, the present study aims to study the hormonal relationships of the hypothalamic-pituitary-adrenal axis, in particular, the glucocorticoid relationship on prolactin secretion as a function of the reproductive experience in females during lactation. The results show that reproductive experience may be a factor modifying the sensitivity of the neuroendocrine response of prolactin secretion to glucocorticoids. However, more studies are needed to understand the possible mechanisms involved, as well as possible modifications in this response as a function of the reproductive status of the females.http://www.seasinop.com.br/revista/index.php?journal=SEA&page=article&op=view&path%5B%5D=458&path%5B%5D=pdfProlactinaadrenalectomiacorticosteróidesdopaminalactação |
spellingShingle | C. D. C. Sanches B. S. Moretti R. C. A. Berber E. E. T. S. Hucke EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS Scientific Electronic Archives Prolactina adrenalectomia corticosteróides dopamina lactação |
title | EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS |
title_full | EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS |
title_fullStr | EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS |
title_full_unstemmed | EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS |
title_short | EFFECT OF ADRENALECTOMY ON PROLACTIN SECRETION IN PRIMIPAROUS AND MULTIPAROUS LACTATING RATS |
title_sort | effect of adrenalectomy on prolactin secretion in primiparous and multiparous lactating rats |
topic | Prolactina adrenalectomia corticosteróides dopamina lactação |
url | http://www.seasinop.com.br/revista/index.php?journal=SEA&page=article&op=view&path%5B%5D=458&path%5B%5D=pdf |
work_keys_str_mv | AT cdcsanches effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats AT bsmoretti effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats AT rcaberber effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats AT eetshucke effectofadrenalectomyonprolactinsecretioninprimiparousandmultiparouslactatingrats |