Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing Wounds

The treatment of long-term non-healing wounds in the conditions of purulent surgery departments, widely uses solutions of chemotherapeutic and antiseptic agents. The most common are the solutions of 3–6 % hydrogen peroxide and solutions of 2–10 % sodium chloride. As a rule, solutions of these drugs...

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Main Authors: V. P. Bodduluri, K. G. Gurevich, A. L. Urakov
Format: Article
Language:English
Published: Bashkir State Medical University 2021-10-01
Series:Креативная хирургия и онкология
Subjects:
Online Access:https://www.surgonco.ru/jour/article/view/608
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author V. P. Bodduluri
K. G. Gurevich
A. L. Urakov
author_facet V. P. Bodduluri
K. G. Gurevich
A. L. Urakov
author_sort V. P. Bodduluri
collection DOAJ
description The treatment of long-term non-healing wounds in the conditions of purulent surgery departments, widely uses solutions of chemotherapeutic and antiseptic agents. The most common are the solutions of 3–6 % hydrogen peroxide and solutions of 2–10 % sodium chloride. As a rule, solutions of these drugs are used to treat non-healing, particularly, purulent wounds, bedsores and trophic ulcers. Therefore, solutions are injected into the wound area repeatedly in the form of course therapy. The findings show that the mechanism of action of these drugs and the effect of treating long-term non-healing wounds is largely determined by such physical and chemical factors of their local interaction as concentration of the main ingredients, osmotic, alkaline activity and local temperature. The findings point out the leading role of the local temperature and the dependence of the local effect on the concentration. They describe the essence of the innovative method of treatment.
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spelling doaj.art-12604e3a6b624cb6abec37ecc835b46b2023-03-13T10:01:10ZengBashkir State Medical UniversityКреативная хирургия и онкология2307-05012076-30932021-10-0111325625910.24060/2076-3093-2021-11-3-256-259444Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing WoundsV. P. Bodduluri0K. G. Gurevich1A. L. Urakov2Фармацевтический институт КравиМосковский государственный медико-стоматологический университет имени А.И. ЕвдокимоваИжевская государственная медицинская академияThe treatment of long-term non-healing wounds in the conditions of purulent surgery departments, widely uses solutions of chemotherapeutic and antiseptic agents. The most common are the solutions of 3–6 % hydrogen peroxide and solutions of 2–10 % sodium chloride. As a rule, solutions of these drugs are used to treat non-healing, particularly, purulent wounds, bedsores and trophic ulcers. Therefore, solutions are injected into the wound area repeatedly in the form of course therapy. The findings show that the mechanism of action of these drugs and the effect of treating long-term non-healing wounds is largely determined by such physical and chemical factors of their local interaction as concentration of the main ingredients, osmotic, alkaline activity and local temperature. The findings point out the leading role of the local temperature and the dependence of the local effect on the concentration. They describe the essence of the innovative method of treatment.https://www.surgonco.ru/jour/article/view/608гнойная хирургиятрофические язвыантисептические средствасанирование гнойных рантемператураперекись водороданатрий хлорид
spellingShingle V. P. Bodduluri
K. G. Gurevich
A. L. Urakov
Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing Wounds
Креативная хирургия и онкология
гнойная хирургия
трофические язвы
антисептические средства
санирование гнойных ран
температура
перекись водорода
натрий хлорид
title Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing Wounds
title_full Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing Wounds
title_fullStr Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing Wounds
title_full_unstemmed Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing Wounds
title_short Physico-Chemical Properties of Antiseptics in Surgery: What is not Taken into Account in Treating Long-Term Non-Healing Wounds
title_sort physico chemical properties of antiseptics in surgery what is not taken into account in treating long term non healing wounds
topic гнойная хирургия
трофические язвы
антисептические средства
санирование гнойных ран
температура
перекись водорода
натрий хлорид
url https://www.surgonco.ru/jour/article/view/608
work_keys_str_mv AT vpbodduluri physicochemicalpropertiesofantisepticsinsurgerywhatisnottakenintoaccountintreatinglongtermnonhealingwounds
AT kggurevich physicochemicalpropertiesofantisepticsinsurgerywhatisnottakenintoaccountintreatinglongtermnonhealingwounds
AT alurakov physicochemicalpropertiesofantisepticsinsurgerywhatisnottakenintoaccountintreatinglongtermnonhealingwounds