Feiyanning formula modulates the molecular mechanism of osimertinib resistance in lung cancer by regulating the Wnt/β-catenin pathway

Feiyanning formula modulates the molecular mechanism of osimertinib resistance in lung cancer by regulating the Wnt/β-catenin pathway

Feiyanning Formula (FYN), a Chinese herbal formula derived from summarized clinical experience, is proven to have anti-tumor effects in lung cancer patients. Osimertinib, a third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI), can improve progression-free survival a...

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Bibliographic Details
Main Authors: Shuliu Sang, Chenbing Sun, Rongzhen Ding, Jingjie Jiang, Yang Han, Shanshan Gan, Ling Bi, Yabin Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
Feiyanning formula
osimertinib
drug resistance
lung cancer
Wnt/β-catenin pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1019451/full

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