Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes

Re-interventions after pulmonary autograft aortic valve replacement (Ross procedure) may be associated with dysfunction of the neoaortic, neopulmonary, or both operated valves. Late dysfunction, other than infective endocarditis, is associated with underlying conditions, technical errors, and unsuit...

Full description

Bibliographic Details
Main Authors: R. M. Muratov, M. I. Fedoseykina, D. A. Titov, D. V. Britikov, G. A. Khugaev
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2021-04-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/1321
_version_ 1797871909613862912
author R. M. Muratov
M. I. Fedoseykina
D. A. Titov
D. V. Britikov
G. A. Khugaev
author_facet R. M. Muratov
M. I. Fedoseykina
D. A. Titov
D. V. Britikov
G. A. Khugaev
author_sort R. M. Muratov
collection DOAJ
description Re-interventions after pulmonary autograft aortic valve replacement (Ross procedure) may be associated with dysfunction of the neoaortic, neopulmonary, or both operated valves. Late dysfunction, other than infective endocarditis, is associated with underlying conditions, technical errors, and unsuitable pulmonary trunk replacement materials. Re-interventions are technically complex, while tactical approaches have not been definitively formulated. Objective: to analyze re-interventions in patients after Ross procedure, technical approaches and immediate outcomes. Material and methods. Between 2001 and 2019, 14 patients were reoperated upon within 2 days to 21 years after primary Ross procedure. Early prosthetic endocarditis (2) and technical errors (1) were the reasons for early postoperative re-intervention. Neoaortic valve insufficiency (7), including pulmonary valve dysfunction (2), pulmonary valve degeneration (2), pulmonary prosthetic valve endocarditis (1), aortic, pulmonary and mitral valve endocarditis (1) were the reasons for late postoperative re-intervention. Based on the lesion volume, neoaortic valve replacement (3), neoaortic root replacement (6), including pulmonary valve/trunk replacement (8), and pulmonary trunk stenting (2) were performed. Results. In-hospital mortality was 7.1%. One patient died of early endocarditis after primary procedure. The postoperative period for the remaining patients was uneventful. Microscopic examination of the neoaorta revealed fragmentation of elastic fibers and rearrangement of tissue histoarchitectonics. In the pulmonary position, the aortic allograft and stentless xenograft had severe calcification and valve stenosis. Conclusions. Neoaortic valve insufficiency associated with cusp prolapse and neoaortic root dilatation may be the reasons for re-interventions after the Ross procedure. The second reason for re-interventions is valve graft dysfunction in the pulmonary trunk position. Elective reoperations on the neoaortic root and/or lung graft, despite the large volume, can be performed with low mortality and morbidity. Aortic allografts and xenografts for reconstruction of the right ventricular outflow tract (RVOT) is unjustified due to early and more severe dysfunction compared to pulmonary allograft.
first_indexed 2024-04-10T00:51:33Z
format Article
id doaj.art-126a0f713827409d91d9aa7b3eb7b79f
institution Directory Open Access Journal
issn 1995-1191
language Russian
last_indexed 2024-04-10T00:51:33Z
publishDate 2021-04-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Vestnik Transplantologii i Iskusstvennyh Organov
spelling doaj.art-126a0f713827409d91d9aa7b3eb7b79f2023-03-13T10:37:27ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912021-04-0123110111110.15825/1995-1191-2021-1-101-111962Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomesR. M. Muratov0M. I. Fedoseykina1D. A. Titov2D. V. Britikov3G. A. Khugaev4Bakulev National Medical Research Center for Cardiovascular SurgeryBakulev National Medical Research Center for Cardiovascular SurgeryBakulev National Medical Research Center for Cardiovascular SurgeryBakulev National Medical Research Center for Cardiovascular SurgeryBakulev National Medical Research Center for Cardiovascular SurgeryRe-interventions after pulmonary autograft aortic valve replacement (Ross procedure) may be associated with dysfunction of the neoaortic, neopulmonary, or both operated valves. Late dysfunction, other than infective endocarditis, is associated with underlying conditions, technical errors, and unsuitable pulmonary trunk replacement materials. Re-interventions are technically complex, while tactical approaches have not been definitively formulated. Objective: to analyze re-interventions in patients after Ross procedure, technical approaches and immediate outcomes. Material and methods. Between 2001 and 2019, 14 patients were reoperated upon within 2 days to 21 years after primary Ross procedure. Early prosthetic endocarditis (2) and technical errors (1) were the reasons for early postoperative re-intervention. Neoaortic valve insufficiency (7), including pulmonary valve dysfunction (2), pulmonary valve degeneration (2), pulmonary prosthetic valve endocarditis (1), aortic, pulmonary and mitral valve endocarditis (1) were the reasons for late postoperative re-intervention. Based on the lesion volume, neoaortic valve replacement (3), neoaortic root replacement (6), including pulmonary valve/trunk replacement (8), and pulmonary trunk stenting (2) were performed. Results. In-hospital mortality was 7.1%. One patient died of early endocarditis after primary procedure. The postoperative period for the remaining patients was uneventful. Microscopic examination of the neoaorta revealed fragmentation of elastic fibers and rearrangement of tissue histoarchitectonics. In the pulmonary position, the aortic allograft and stentless xenograft had severe calcification and valve stenosis. Conclusions. Neoaortic valve insufficiency associated with cusp prolapse and neoaortic root dilatation may be the reasons for re-interventions after the Ross procedure. The second reason for re-interventions is valve graft dysfunction in the pulmonary trunk position. Elective reoperations on the neoaortic root and/or lung graft, despite the large volume, can be performed with low mortality and morbidity. Aortic allografts and xenografts for reconstruction of the right ventricular outflow tract (RVOT) is unjustified due to early and more severe dysfunction compared to pulmonary allograft.https://journal.transpl.ru/vtio/article/view/1321ross procedureautograftallograftaortic valvereoperation
spellingShingle R. M. Muratov
M. I. Fedoseykina
D. A. Titov
D. V. Britikov
G. A. Khugaev
Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes
Vestnik Transplantologii i Iskusstvennyh Organov
ross procedure
autograft
allograft
aortic valve
reoperation
title Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes
title_full Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes
title_fullStr Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes
title_full_unstemmed Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes
title_short Re-interventions after the Ross procedure: reasons, technical approaches, immediate outcomes
title_sort re interventions after the ross procedure reasons technical approaches immediate outcomes
topic ross procedure
autograft
allograft
aortic valve
reoperation
url https://journal.transpl.ru/vtio/article/view/1321
work_keys_str_mv AT rmmuratov reinterventionsaftertherossprocedurereasonstechnicalapproachesimmediateoutcomes
AT mifedoseykina reinterventionsaftertherossprocedurereasonstechnicalapproachesimmediateoutcomes
AT datitov reinterventionsaftertherossprocedurereasonstechnicalapproachesimmediateoutcomes
AT dvbritikov reinterventionsaftertherossprocedurereasonstechnicalapproachesimmediateoutcomes
AT gakhugaev reinterventionsaftertherossprocedurereasonstechnicalapproachesimmediateoutcomes